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Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J, Sánchez IDM, Yasmeen A, Diaz M, Aldon Y, Bijl TPL, Venkatayogi S, Martin Beem JS, Newman A, Jiang C, Lee WH, Pater M, Burger JA, van Breemen MJ, de Taeye SW, Rantalainen K, LaBranche C, Saunders KO, Montefiori D, Ozorowski G, Ward AB, Crispin M, Moore JP, Klasse PJ, Haynes BF, Wilson IA, Wiehe K, Verkoczy L, Sanders RW. Caniels TG, et al. Among authors: haynes bf. Cell Rep Med. 2023 Apr 18;4(4):101003. doi: 10.1016/j.xcrm.2023.101003. Epub 2023 Apr 11. Cell Rep Med. 2023. PMID: 37044090 Free PMC article.
Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles.
Mu Z, Wiehe K, Saunders KO, Henderson R, Cain DW, Parks R, Martik D, Mansouri K, Edwards RJ, Newman A, Lu X, Xia SM, Bonsignori M, Montefiori D, Han Q, Venkatayogi S, Evangelous T, Wang Y, Rountree W, Tam Y, Barbosa C, Alam SM, Williams WB, Pardi N, Weissman D, Haynes BF. Mu Z, et al. Among authors: haynes bf. bioRxiv [Preprint]. 2021 Aug 9:2021.08.09.455714. doi: 10.1101/2021.08.09.455714. bioRxiv. 2021. PMID: 34401876 Free PMC article. Preprint.
Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor.
Pilewski KA, Wall S, Richardson SI, Manamela NP, Clark K, Hermanus T, Binshtein E, Venkat R, Sautto GA, Kramer KJ, Shiakolas AR, Setliff I, Salas J, Mapengo RE, Suryadevara N, Brannon JR, Beebout CJ, Parks R, Raju N, Frumento N, Walker LM, Fechter EF, Qin JS, Murji AA, Janowska K, Thakur B, Lindenberger J, May AJ, Huang X, Sammour S, Acharya P, Carnahan RH, Ross TM, Haynes BF, Hadjifrangiskou M, Crowe JE Jr, Bailey JR, Kalams S, Morris L, Georgiev IS. Pilewski KA, et al. Among authors: haynes bf. Cell Rep. 2023 Feb 28;42(2):112044. doi: 10.1016/j.celrep.2023.112044. Epub 2023 Jan 27. Cell Rep. 2023. PMID: 36708513 Free PMC article.
Microsecond dynamics control the HIV-1 envelope conformation.
Bennett AL, Edwards RJ, Kosheleva I, Saunders C, Bililign Y, Williams A, Manosouri K, Saunders KO, Haynes BF, Acharya P, Henderson R. Bennett AL, et al. Among authors: haynes bf. bioRxiv [Preprint]. 2023 May 18:2023.05.17.541130. doi: 10.1101/2023.05.17.541130. bioRxiv. 2023. Update in: Sci Adv. 2024 Feb 2;10(5):eadj0396. doi: 10.1126/sciadv.adj0396 PMID: 37292605 Free PMC article. Updated. Preprint.
Non-neutralizing SARS-CoV-2 N-terminal domain antibodies protect mice against severe disease using Fc-mediated effector functions.
Pierre CN, Adams LE, Anasti K, Goodman D, Stanfield-Oakley S, Powers JM, Li D, Rountree W, Wang Y, Edwards RJ, Munir Alam S, Ferrari G, Tomaras GD, Haynes BF, Baric RS, Saunders KO. Pierre CN, et al. Among authors: haynes bf. bioRxiv [Preprint]. 2023 Jul 26:2023.07.25.550460. doi: 10.1101/2023.07.25.550460. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Jun 20;20(6):e1011569. doi: 10.1371/journal.ppat.1011569 PMID: 37546738 Free PMC article. Updated. Preprint.
Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.
Vanover D, Zurla C, Peck HE, Orr-Burks N, Joo JY, Murray J, Holladay N, Hobbs RA, Jung Y, Chaves LCS, Rotolo L, Lifland AW, Olivier AK, Li D, Saunders KO, Sempowski GD, Crowe JE Jr, Haynes BF, Lafontaine ER, Hogan RJ, Santangelo PJ. Vanover D, et al. Among authors: haynes bf. Adv Sci (Weinh). 2022 Dec;9(34):e2202771. doi: 10.1002/advs.202202771. Epub 2022 Oct 31. Adv Sci (Weinh). 2022. PMID: 36316224 Free PMC article.
The other pandemic: lessons from 40 years of HIV research.
Klotman ME, Haynes BF. Klotman ME, et al. Among authors: haynes bf. J Clin Invest. 2024 Jul 1;134(13):e183039. doi: 10.1172/JCI183039. J Clin Invest. 2024. PMID: 38949029 Free PMC article. No abstract available.
783 results