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A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi.
Dos Reis TF, de Castro PA, Bastos RW, Pinzan CF, Souza PFN, Ackloo S, Hossain MA, Drewry DH, Alkhazraji S, Ibrahim AS, Jo H, Lightfoot JD, Adams EM, Fuller KK, deGrado WF, Goldman GH. Dos Reis TF, et al. Among authors: drewry dh. Nat Commun. 2023 Apr 12;14(1):2052. doi: 10.1038/s41467-023-37573-y. Nat Commun. 2023. PMID: 37045836 Free PMC article.
CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model.
Ketley A, Wojciechowska M, Ghidelli-Disse S, Bamborough P, Ghosh TK, Morato ML, Sedehizadeh S, Malik NA, Tang Z, Powalowska P, Tanner M, Billeter-Clark R, Trueman RC, Geiszler PC, Agostini A, Othman O, Bösche M, Bantscheff M, Rüdiger M, Mossakowska DE, Drewry DH, Zuercher WJ, Thornton CA, Drewes G, Uings I, Hayes CJ, Brook JD. Ketley A, et al. Among authors: drewry dh. Sci Transl Med. 2020 Apr 29;12(541):eaaz2415. doi: 10.1126/scitranslmed.aaz2415. Sci Transl Med. 2020. PMID: 32350131
Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
Chen P, Chaikuad A, Bamborough P, Bantscheff M, Bountra C, Chung CW, Fedorov O, Grandi P, Jung D, Lesniak R, Lindon M, Müller S, Philpott M, Prinjha R, Rogers C, Selenski C, Tallant C, Werner T, Willson TM, Knapp S, Drewry DH. Chen P, et al. Among authors: drewry dh. J Med Chem. 2016 Feb 25;59(4):1410-24. doi: 10.1021/acs.jmedchem.5b00209. Epub 2015 Apr 6. J Med Chem. 2016. PMID: 25799074 Free PMC article.
Solid-supported reagents in organic synthesis.
Drewry DH, Coe DM, Poon S. Drewry DH, et al. Med Res Rev. 1999 Mar;19(2):97-148. doi: 10.1002/(sici)1098-1128(199903)19:2<97::aid-med2>3.0.co;2-y. Med Res Rev. 1999. PMID: 10189175 Review.
118 results