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Page 1
Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
Thienel M, Müller-Reif JB, Zhang Z, Ehreiser V, Huth J, Shchurovska K, Kilani B, Schweizer L, Geyer PE, Zwiebel M, Novotny J, Lüsebrink E, Little G, Orban M, Nicolai L, El Nemr S, Titova A, Spannagl M, Kindberg J, Evans AL, Mach O, Vogel M, Tiedt S, Ormanns S, Kessler B, Dueck A, Friebe A, Jørgensen PG, Majzoub-Altweck M, Blutke A, Polzin A, Stark K, Kääb S, Maier D, Gibbins JM, Limper U, Frobert O, Mann M, Massberg S, Petzold T. Thienel M, et al. Among authors: titova a. Science. 2023 Apr 14;380(6641):178-187. doi: 10.1126/science.abo5044. Epub 2023 Apr 13. Science. 2023. PMID: 37053338
Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.
Novotny J, Chandraratne S, Weinberger T, Philippi V, Stark K, Ehrlich A, Pircher J, Konrad I, Oberdieck P, Titova A, Hoti Q, Schubert I, Legate KR, Urtz N, Lorenz M, Pelisek J, Massberg S, von Brühl ML, Schulz C. Novotny J, et al. Among authors: titova a. PLoS One. 2018 Jan 2;13(1):e0190728. doi: 10.1371/journal.pone.0190728. eCollection 2018. PLoS One. 2018. PMID: 29293656 Free PMC article.
Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.
Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C. Pircher J, et al. Among authors: titova a. Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2. Nat Commun. 2018. PMID: 29670076 Free PMC article.
Thrombus NET content is associated with clinical outcome in stroke and myocardial infarction.
Novotny J, Oberdieck P, Titova A, Pelisek J, Chandraratne S, Nicol P, Hapfelmeier A, Joner M, Maegdefessel L, Poppert H, Pircher J, Massberg S, Friedrich B, Zimmer C, Schulz C, Boeckh-Behrens T. Novotny J, et al. Among authors: titova a. Neurology. 2020 Jun 2;94(22):e2346-e2360. doi: 10.1212/WNL.0000000000009532. Epub 2020 May 20. Neurology. 2020. PMID: 32434865
Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.
Kaiser R, Leunig A, Pekayvaz K, Popp O, Joppich M, Polewka V, Escaig R, Anjum A, Hoffknecht ML, Gold C, Brambs S, Engel A, Stockhausen S, Knottenberg V, Titova A, Haji M, Scherer C, Muenchhoff M, Hellmuth JC, Saar K, Schubert B, Hilgendorff A, Schulz C, Kääb S, Zimmer R, Hübner N, Massberg S, Mertins P, Nicolai L, Stark K. Kaiser R, et al. Among authors: titova a. JCI Insight. 2021 Sep 22;6(18):e150862. doi: 10.1172/jci.insight.150862. JCI Insight. 2021. PMID: 34403366 Free PMC article.
Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI.
Kaiser R, Escaig R, Kranich J, Hoffknecht ML, Anjum A, Polewka V, Mader M, Hu W, Belz L, Gold C, Titova A, Lorenz M, Pekayvaz K, Kääb S, Gaertner F, Stark K, Brocker T, Massberg S, Nicolai L. Kaiser R, et al. Among authors: titova a. Blood. 2022 Jul 14;140(2):121-139. doi: 10.1182/blood.2021014914. Blood. 2022. PMID: 35472164 Free PMC article.
Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration.
Nicolai L, Leunig A, Pekayvaz K, Esefeld M, Anjum A, Rath J, Riedlinger E, Ehreiser V, Mader M, Eivers L, Hoffknecht ML, Zhang Z, Kugelmann D, Rossaro D, Escaig R, Kaiser R, Polewka V, Titova A, Petzold T, Spiekermann K, Iannacone M, Thiele T, Greinacher A, Stark K, Massberg S. Nicolai L, et al. Among authors: titova a. Blood. 2022 Aug 4;140(5):478-490. doi: 10.1182/blood.2021014712. Blood. 2022. PMID: 35486845 Free PMC article.
Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.
Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez-Navarro A, Eivers L, Coletti R, Joppich M, Dionísio F, Kaiser R, Tomas L, Janjic A, Knott M, Mehari F, Polewka V, Kirschner M, Boda A, Nicolai L, Schulz H, Titova A, Kilani B, Lorenz M, Fingerle-Rowson G, Bucala R, Enard W, Zimmer R, Weber C, Libby P, Schulz C, Massberg S, Stark K. Pekayvaz K, et al. Among authors: titova a. Immunity. 2023 Oct 10;56(10):2325-2341.e15. doi: 10.1016/j.immuni.2023.08.002. Epub 2023 Aug 30. Immunity. 2023. PMID: 37652021 Free PMC article.
Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis.
Gaertner F, Ishikawa-Ankerhold H, Stutte S, Fu W, Weitz J, Dueck A, Nelakuditi B, Fumagalli V, van den Heuvel D, Belz L, Sobirova G, Zhang Z, Titova A, Navarro AM, Pekayvaz K, Lorenz M, von Baumgarten L, Kranich J, Straub T, Popper B, Zheden V, Kaufmann WA, Guo C, Piontek G, von Stillfried S, Boor P, Colonna M, Clauß S, Schulz C, Brocker T, Walzog B, Scheiermann C, Aird WC, Nerlov C, Stark K, Petzold T, Engelhardt S, Sixt M, Hauschild R, Rudelius M, Oostendorp RAJ, Iannacone M, Heinig M, Massberg S. Gaertner F, et al. Among authors: titova a. Nature. 2024 Jul;631(8021):645-653. doi: 10.1038/s41586-024-07671-y. Epub 2024 Jul 10. Nature. 2024. PMID: 38987596 Free PMC article.
113 results