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Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation.
Shen H, Liu T, Jiang H, Titsch C, Taylor K, Kandoussi H, Qiu X, Chen C, Sukrutharaj S, Kuit K, Mintier G, Krishnamurthy P, Fancher RM, Zeng J, Rodrigues AD, Marathe P, Lai Y. Shen H, et al. Among authors: lai y. Drug Metab Dispos. 2016 Feb;44(2):238-49. doi: 10.1124/dmd.115.066852. Epub 2015 Nov 25. Drug Metab Dispos. 2016. PMID: 26608080
Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics.
Wang L, Collins C, Kelly EJ, Chu X, Ray AS, Salphati L, Xiao G, Lee C, Lai Y, Liao M, Mathias A, Evers R, Humphreys W, Hop CE, Kumer SC, Unadkat JD. Wang L, et al. Among authors: lai y. Drug Metab Dispos. 2016 Nov;44(11):1752-1758. doi: 10.1124/dmd.116.071050. Epub 2016 Aug 19. Drug Metab Dispos. 2016. PMID: 27543206 Free PMC article.
Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics.
Billington S, Ray AS, Salphati L, Xiao G, Chu X, Humphreys WG, Liao M, Lee CA, Mathias A, Hop CECA, Rowbottom C, Evers R, Lai Y, Kelly EJ, Prasad B, Unadkat JD. Billington S, et al. Among authors: lai y. Drug Metab Dispos. 2018 Feb;46(2):189-196. doi: 10.1124/dmd.117.077289. Epub 2017 Nov 14. Drug Metab Dispos. 2018. PMID: 29138286 Free PMC article.
Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys.
Shen H, Nelson DM, Oliveira RV, Zhang Y, Mcnaney CA, Gu X, Chen W, Su C, Reily MD, Shipkova PA, Gan J, Lai Y, Marathe P, Humphreys WG. Shen H, et al. Among authors: lai y. Drug Metab Dispos. 2018 Feb;46(2):178-188. doi: 10.1124/dmd.117.077586. Epub 2017 Nov 21. Drug Metab Dispos. 2018. PMID: 29162614
9,674 results