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Page 1
Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study.
Howard JF Jr, Bresch S, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Lowcock R, Vanderkelen M, Leite MI; RAISE Study Team. Howard JF Jr, et al. Among authors: hinton j. Lancet Neurol. 2023 May;22(5):395-406. doi: 10.1016/S1474-4422(23)00080-7. Lancet Neurol. 2023. PMID: 37059508 Clinical Trial.
Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial.
Howard JF Jr, Nowak RJ, Wolfe GI, Freimer ML, Vu TH, Hinton JL, Benatar M, Duda PW, MacDougall JE, Farzaneh-Far R, Kaminski HJ; Zilucoplan MG Study Group; Barohn R, Dimachkie M, Pasnoor M, Farmakidis C, Liu T, Colgan S, Benatar MG, Bertorini T, Pillai R, Henegar R, Bromberg M, Gibson S, Janecki T, Freimer M, Elsheikh B, Matisak P, Genge A, Guidon A, David W, Habib AA, Mathew V, Mozaffar T, Hinton JL, Hewitt W, Barnett D, Sullivan P, Ho D, Howard JF Jr, Traub RE, Chopra M, Kaminski HJ, Aly R, Bayat E, Abu-Rub M, Khan S, Lange D, Holzberg S, Khatri B, Lindman E, Olapo T, Sershon LM, Lisak RP, Bernitsas E, Jia K, Malik R, Lewis-Collins TD, Nicolle M, Nowak RJ, Sharma A, Roy B, Nye J, Pulley M, Berger A, Shabbir Y, Sachdev A, Patterson K, Siddiqi Z, Sivak M, Bratton J, Small G, Kohli A, Fetter M, Vu T, Lam L, Harvey B, Wolfe GI, Silvestri N, Patrick K, Zakalik K, Duda PW, MacDougall J, Farzaneh-Far R, Pontius A, Hoarty M. Howard JF Jr, et al. Among authors: hinton jl. JAMA Neurol. 2020 May 1;77(5):582-592. doi: 10.1001/jamaneurol.2019.5125. JAMA Neurol. 2020. PMID: 32065623 Free PMC article. Clinical Trial.
Long-term safety and efficacy of zilucoplan in patients with generalized myasthenia gravis: interim analysis of the RAISE-XT open-label extension study.
Howard JF Jr, Bresch S, Farmakidis C, Freimer M, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Nowak RJ, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Bloemers J, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Vanderkelen M, Leite MI; RAISE-XT Study Team*. Howard JF Jr, et al. Among authors: hinton j. Ther Adv Neurol Disord. 2024 Apr 17;17:17562864241243186. doi: 10.1177/17562864241243186. eCollection 2024. Ther Adv Neurol Disord. 2024. PMID: 38638673 Free PMC article.
A brain-wide map of descending inputs onto spinal V1 interneurons.
Chapman PD, Kulkarni AS, Trevisan AJ, Han K, Hinton JM, Deltuvaite P, Fenno LE, Ramakrishnan C, Patton MH, Schwarz LA, Zakharenko SS, Deisseroth K, Bikoff JB. Chapman PD, et al. Among authors: hinton jm. Neuron. 2024 Dec 19:S0896-6273(24)00876-6. doi: 10.1016/j.neuron.2024.11.019. Online ahead of print. Neuron. 2024. PMID: 39719703
Intrinsic and environmental drivers of pairwise cohesion in wild Canis social groups.
Benson JF, Keiter DA, Mahoney PJ, Allen BL, Allen L, Álvares F, Anderson ML, Barber-Meyer SM, Barocas A, Beasley JC, Behrendorff L, Belant JL, Beyer DE Jr, Boitani L, Borg BL, Boutin S, Boydston EE, Brown JL, Bump JK, Cepek JD, Chamberlain MJ, Chenaux-Ibrahim YM, Cherry SG, Ćirović D, Ciucci P, Cluff HD, Cooper SM, Crooks KR, Dupont DLJ, Fisher RN, Fortin D, Gable TD, García E, Geffen E, Gehrt SD, Gillingham M, Heard DC, Hebblewhite M, Hinton JW, Homkes AT, Howden CG, Huber D, Jackson PJ, Joly K, Kelly A, Kelly MJ, Kingdon KA, Kulkarni A, Kusak J, Kuzyk GW, Lake BC, Llaneza L, López-Bao JV, MacNulty DR, McLaren AAD, McLoughlin PD, Merrill EH, Mills KJ, Mitchell N, Moore SA, Mumma MA, Murray MH, Musiani M, Nakamura M, Neilson EW, Neufeld LM, Newsome TM, Oakleaf JK, Palacios V, Perdicas MM, Perry T, Petroelje TR, Piper CB, Prokopenko CM, Prugh LR, Riley SPD, Rio-Maior H, Roffler GH, Rollins D, Sand H, Schmiegelow FKA, Seip DR, Sorum MS, St Clair CC, Steenweg R, Strohbach MW, Tatler J, Thaker M, Thompson CA, Turner JW, Vanak AT, Vander Wal E, Wabakken P, Walter SE, Webster SC, Wheeldon TJ, Wikenros C, Windels SK, Young JK, Zabihi-Seissan S, Zimmermann B, Patterson BR. Benson JF, et al. Among authors: hinton jw. Ecology. 2024 Dec 12:e4492. doi: 10.1002/ecy.4492. Online ahead of print. Ecology. 2024. PMID: 39663892
Ultra-high-energy gamma-ray bubble around microquasar V4641 Sgr.
Alfaro R, Alvarez C, Arteaga-Velázquez JC, Avila Rojas D, Ayala Solares HA, Babu R, Belmont-Moreno E, Caballero-Mora KS, Capistrán T, Carramiñana A, Casanova S, Cotti U, Cotzomi J, Coutiño de León S, De la Fuente E, Depaoli D, Di Lalla N, Diaz Hernandez R, Dingus BL, DuVernois MA, Durocher M, Díaz-Vélez JC, Engel K, Espinoza C, Fan KL, Fang K, Fraija N, Fraija S, García-González JA, Garfias F, Gonzalez Muñoz A, González MM, Goodman JA, Groetsch S, Harding JP, Herzog I, Hinton J, Huang D, Hueyotl-Zahuantitla F, Hüntemeyer P, Iriarte A, Joshi V, Kaufmann S, Kieda D, de León C, Lee J, León Vargas H, Linnemann JT, Longinotti AL, Luis-Raya G, Malone K, Martinez O, Martínez-Castro J, Matthews JA, Miranda-Romagnoli P, Morales-Soto JA, Moreno E, Mostafá M, Nayerhoda A, Nellen L, Newbold M, Nisa MU, Noriega-Papaqui R, Olivera-Nieto L, Omodei N, Osorio M, Pérez Araujo Y, Pérez-Pérez EG, Rho CD, Rosa-González D, Ruiz-Velasco E, Salazar H, Salazar-Gallegos D, Sandoval A, Schneider M, Serna-Franco J, Smith AJ, Son Y, Springer RW, Tibolla O, Tollefson K, Torres I, Torres-Escobedo R, Turner R, Ureña-Mena F, Varela E, Villaseñor L, Wang X, Watson IJ, Willox E, Yun-Cárcamo S, Zhou H. Alfaro R, et al. Among authors: hinton j. Nature. 2024 Oct;634(8034):557-560. doi: 10.1038/s41586-024-07995-9. Epub 2024 Oct 16. Nature. 2024. PMID: 39415065
740 results