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Top-down design of protein architectures with reinforcement learning.
Lutz ID, Wang S, Norn C, Courbet A, Borst AJ, Zhao YT, Dosey A, Cao L, Xu J, Leaf EM, Treichel C, Litvicov P, Li Z, Goodson AD, Rivera-Sánchez P, Bratovianu AM, Baek M, King NP, Ruohola-Baker H, Baker D. Lutz ID, et al. Among authors: baker d. Science. 2023 Apr 21;380(6642):266-273. doi: 10.1126/science.adf6591. Epub 2023 Apr 20. Science. 2023. PMID: 37079676
Progress in modeling of protein structures and interactions.
Schueler-Furman O, Wang C, Bradley P, Misura K, Baker D. Schueler-Furman O, et al. Among authors: baker d. Science. 2005 Oct 28;310(5748):638-42. doi: 10.1126/science.1112160. Science. 2005. PMID: 16254179 Review.
A putative Src homology 3 domain binding motif but not the C-terminal dystrophin WW domain binding motif is required for dystroglycan function in cellular polarity in Drosophila.
Yatsenko AS, Gray EE, Shcherbata HR, Patterson LB, Sood VD, Kucherenko MM, Baker D, Ruohola-Baker H. Yatsenko AS, et al. Among authors: baker d. J Biol Chem. 2007 May 18;282(20):15159-69. doi: 10.1074/jbc.M608800200. Epub 2007 Mar 12. J Biol Chem. 2007. PMID: 17355978 Free article.
De novo computational design of retro-aldol enzymes.
Jiang L, Althoff EA, Clemente FR, Doyle L, Röthlisberger D, Zanghellini A, Gallaher JL, Betker JL, Tanaka F, Barbas CF 3rd, Hilvert D, Houk KN, Stoddard BL, Baker D. Jiang L, et al. Among authors: baker d. Science. 2008 Mar 7;319(5868):1387-91. doi: 10.1126/science.1152692. Science. 2008. PMID: 18323453 Free PMC article.
NMR structure determination for larger proteins using backbone-only data.
Raman S, Lange OF, Rossi P, Tyka M, Wang X, Aramini J, Liu G, Ramelot TA, Eletsky A, Szyperski T, Kennedy MA, Prestegard J, Montelione GT, Baker D. Raman S, et al. Among authors: baker d. Science. 2010 Feb 19;327(5968):1014-8. doi: 10.1126/science.1183649. Epub 2010 Feb 4. Science. 2010. PMID: 20133520 Free PMC article.
5,806 results