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Page 1
Top-down design of protein architectures with reinforcement learning.
Lutz ID, Wang S, Norn C, Courbet A, Borst AJ, Zhao YT, Dosey A, Cao L, Xu J, Leaf EM, Treichel C, Litvicov P, Li Z, Goodson AD, Rivera-Sánchez P, Bratovianu AM, Baek M, King NP, Ruohola-Baker H, Baker D. Lutz ID, et al. Among authors: treichel c. Science. 2023 Apr 21;380(6642):266-273. doi: 10.1126/science.adf6591. Epub 2023 Apr 20. Science. 2023. PMID: 37079676
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Lee J, Zepeda SK, Park YJ, Taylor AL, Quispe J, Stewart C, Leaf EM, Treichel C, Corti D, King NP, Starr TN, Veesler D. Lee J, et al. Among authors: treichel c. bioRxiv [Preprint]. 2023 Sep 13:2023.09.12.557371. doi: 10.1101/2023.09.12.557371. bioRxiv. 2023. Update in: Cell Host Microbe. 2023 Dec 13;31(12):1961-1973.e11. doi: 10.1016/j.chom.2023.10.018 PMID: 37745523 Free PMC article. Updated. Preprint.
In vivo selection of synthetic nucleocapsids for tissue targeting.
Olshefsky A, Benasutti H, Sylvestre M, Butterfield GL, Rocklin GJ, Richardson C, Hicks DR, Lajoie MJ, Song K, Leaf E, Treichel C, Decarreau J, Ke S, Kher G, Carter L, Chamberlain JS, Baker D, King NP, Pun SH. Olshefsky A, et al. Among authors: treichel c. Proc Natl Acad Sci U S A. 2023 Nov 14;120(46):e2306129120. doi: 10.1073/pnas.2306129120. Epub 2023 Nov 8. Proc Natl Acad Sci U S A. 2023. PMID: 37939083 Free PMC article.
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Lee J, Zepeda SK, Park YJ, Taylor AL, Quispe J, Stewart C, Leaf EM, Treichel C, Corti D, King NP, Starr TN, Veesler D. Lee J, et al. Among authors: treichel c. Cell Host Microbe. 2023 Dec 13;31(12):1961-1973.e11. doi: 10.1016/j.chom.2023.10.018. Epub 2023 Nov 20. Cell Host Microbe. 2023. PMID: 37989312 Free PMC article.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP. Chao CW, et al. Among authors: treichel c. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584735. doi: 10.1101/2024.03.13.584735. bioRxiv. 2024. Update in: Cell Rep. 2024 Dec 24;43(12):115036. doi: 10.1016/j.celrep.2024.115036 PMID: 38558973 Free PMC article. Updated. Preprint.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW, Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG, Ahlrichs M, Dobbins C, Hand A, McGowan J, Simmons B, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schäfer A, Veesler D, King NP. Chao CW, et al. Among authors: treichel c. Cell Rep. 2024 Dec 24;43(12):115036. doi: 10.1016/j.celrep.2024.115036. Epub 2024 Dec 6. Cell Rep. 2024. PMID: 39644492 Free article.
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Lee J, Stewart C, Schaefer A, Leaf EM, Park YJ, Asarnow D, Powers JM, Treichel C, Corti D, Baric R, King NP, Veesler D. Lee J, et al. Among authors: treichel c. bioRxiv [Preprint]. 2023 Dec 20:2023.12.12.571160. doi: 10.1101/2023.12.12.571160. bioRxiv. 2023. Update in: Nat Commun. 2024 Jun 28;15(1):5496. doi: 10.1038/s41467-024-49656-5 PMID: 38168207 Free PMC article. Updated. Preprint.
Computationally designed mRNA-launched protein nanoparticle vaccines.
Hendricks GG, Grigoryan L, Navarro MJ, Catanzaro NJ, Hubbard ML, Powers JM, Mattocks M, Treichel C, Walls AC, Lee J, Ellis D, Wang JYJ, Cheng S, Miranda MC, Valdez A, Chao CW, Chan S, Men C, Johnson MR, Hui H, Wu SY, Lujan V, Muramatsu H, Lin PJC, Sung MMH, Tam YK, Leaf EM, Pardi N, Baric RS, Pulendran B, Veesler D, Schäfer A, King NP. Hendricks GG, et al. Among authors: treichel c. bioRxiv [Preprint]. 2024 Jul 23:2024.07.22.604655. doi: 10.1101/2024.07.22.604655. bioRxiv. 2024. PMID: 39091730 Free PMC article. Preprint.
34 results