de Aquino TM - Search Results

1

Preclinical data on morpholine (3,5-di-tertbutyl-4-hydroxyphenyl) methanone induced anxiolysis.

Cabral IB, de Lima Moreira CV, Rodrigues ACC, da Silva Moreira LK, Pereira JKA, Gomides CD, Lião LM, Machado LS, Vaz BG, da Cunha LC, de Oliveira Neto JR, da Silva-Júnior EF, de Aquino TM, da Silva Santos-Júnior PF, Silva ON, da Rocha FF, Costa EA, Menegatti R, Fajemiroye JO. Cabral IB, et al. Among authors: de lima moreira cv, de aquino tm, de oliveira neto jr. Naunyn Schmiedebergs Arch Pharmacol. 2023 Nov;396(11):2957-2975. doi: 10.1007/s00210-023-02502-9. Epub 2023 Apr 25. Naunyn Schmiedebergs Arch Pharmacol. 2023. PMID: 37097335

2

Antileishmanial activity of new thiophene-indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies.

Félix MB, de Souza ER, de Lima MDCA, Frade DKG, Serafim VL, Rodrigues KADF, Néris PLDN, Ribeiro FF, Scotti L, Scotti MT, de Aquino TM, Mendonça Junior FJB, de Oliveira MR. Félix MB, et al. Among authors: de aquino tm, de oliveira mr, de souza er, de lima mdca. Bioorg Med Chem. 2016 Sep 15;24(18):3972-3977. doi: 10.1016/j.bmc.2016.04.057. Epub 2016 Apr 26. Bioorg Med Chem. 2016. PMID: 27515718 Free article.

3

Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles.

Liesen AP, de Aquino TM, Carvalho CS, Lima VT, de Araújo JM, de Lima JG, de Faria AR, de Melo EJ, Alves AJ, Alves EW, Alves AQ, Góes AJ. Liesen AP, et al. Among authors: de melo ej, de aquino tm, de araujo jm, de lima jg, de faria ar. Eur J Med Chem. 2010 Sep;45(9):3685-91. doi: 10.1016/j.ejmech.2010.05.017. Epub 2010 May 31. Eur J Med Chem. 2010. PMID: 20541294

4

Biological activities and physicochemical characterization of alkaline lignins obtained from branches and leaves of Buchenavia viridiflora with potential pharmaceutical and biomedical applications.

Araújo DMF, da Cruz Filho IJ, Santos T, Pereira DTM, Marques DSC, da Conceição Alves de Lima A, de Aquino TM, de Moraes Rocha GJ, do Carmo Alves de Lima M, Nogueira F. Araújo DMF, et al. Among authors: de aquino tm, de moraes rocha gj. Int J Biol Macromol. 2022 Oct 31;219:224-245. doi: 10.1016/j.ijbiomac.2022.07.225. Epub 2022 Aug 1. Int J Biol Macromol. 2022. PMID: 35926677

5

Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity.

de Araújo RS, Guerra FQ, de O Lima E, de Simone CA, Tavares JF, Scotti L, Scotti MT, de Aquino TM, de Moura RO, Mendonça FJ, Barbosa-Filho JM. de Araújo RS, et al. Among authors: de moura ro, de aquino tm, de simone ca, de o lima e. Int J Mol Sci. 2013 Jan 10;14(1):1293-309. doi: 10.3390/ijms14011293. Int J Mol Sci. 2013. PMID: 23306152 Free PMC article.

6

The influence of N-alkyl chains in benzoyl-thiourea derivatives on urease inhibition: Soil studies and biophysical and theoretical investigations on the mechanism of interaction.

Tavares MC, Dos Santos Nascimento IJ, de Aquino TM, de Oliveira Brito T, Macedo F Jr, Modolo LV, de Fátima Â, Santos JCC. Tavares MC, et al. Among authors: de aquino tm, de fatima a, de oliveira brito t. Biophys Chem. 2023 Aug;299:107042. doi: 10.1016/j.bpc.2023.107042. Epub 2023 May 24. Biophys Chem. 2023. PMID: 37263179

7

2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro.

Rodrigues KA, Dias CN, Néris PL, Rocha Jda C, Scotti MT, Scotti L, Mascarenhas SR, Veras RC, de Medeiros IA, Keesen Tde S, de Oliveira TB, de Lima Mdo C, Balliano TL, de Aquino TM, de Moura RO, Mendonça Junior FJ, de Oliveira MR. Rodrigues KA, et al. Among authors: de moura ro, de aquino tm, de lima mdo c, de oliveira mr, de oliveira tb, de medeiros ia. Eur J Med Chem. 2015 Dec 1;106:1-14. doi: 10.1016/j.ejmech.2015.10.011. Epub 2015 Oct 17. Eur J Med Chem. 2015. PMID: 26513640

8

Molecular Docking Studies Applied to a Dataset of Cruzain Inhibitors.

da Silva-Junior EF, Barcellos Franca PH, Ribeiro FF, Bezerra Mendonca-Junior FJ, Scotti L, Scotti MT, de Aquino TM, de Araujo-Junior JX. da Silva-Junior EF, et al. Among authors: de araujo junior jx, de aquino tm. Curr Comput Aided Drug Des. 2018;14(1):68-78. doi: 10.2174/1573409913666170519112758. Curr Comput Aided Drug Des. 2018. PMID: 28523999

9

Evidence for the involvement of TNF-α, IL-1β and IL-10 in the antinociceptive and anti-inflammatory effects of indole-3-guanylhydrazone hydrochloride, an aromatic aminoguanidine, in rodents.

Sandes SMS, Heimfarth L, Brito RG, Santos PL, Gouveia DN, Carvalho AMS, Quintans JSS, da Silva-Júnior EF, de Aquino TM, França PHB, de Araújo-Júnior JX, Albuquerque-Júnior RLC, Zengin G, Schmitt M, Bourguignon JJ, Quintans-Júnior LJ. Sandes SMS, et al. Among authors: de araujo junior jx, de aquino tm. Chem Biol Interact. 2018 Apr 25;286:1-10. doi: 10.1016/j.cbi.2018.02.026. Epub 2018 Feb 27. Chem Biol Interact. 2018. PMID: 29499192

10

Indole-3-guanylhydrazone hydrochloride mitigates long-term cognitive impairment in a neonatal sepsis model with involvement of MAPK and NFκB pathways.

Heimfarth L, Carvalho AMS, Quintans JSS, Pereira EWM, Lima NT, Bezerra Carvalho MT, Barreto RSS, Moreira JCF, da Silva-Júnior EF, Schmitt M, Bourguignon JJ, de Aquino TM, Araújo-Júnior JX, Quintans-Júnior LJ. Heimfarth L, et al. Among authors: de aquino tm. Neurochem Int. 2020 Mar;134:104647. doi: 10.1016/j.neuint.2019.104647. Epub 2019 Dec 23. Neurochem Int. 2020. PMID: 31877349

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