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Mouse models of neutropenia reveal progenitor-stage-specific defects.
Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL. Muench DE, et al. Among authors: ferchen k. Nature. 2020 Jun;582(7810):109-114. doi: 10.1038/s41586-020-2227-7. Epub 2020 Apr 22. Nature. 2020. PMID: 32494068 Free PMC article.
Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function.
Basu J, Reis BS, Peri S, Zha J, Hua X, Ge L, Ferchen K, Nicolas E, Czyzewicz P, Cai KQ, Tan Y, Fuxman Bass JI, Walhout AJM, Grimes HL, Grivennikov SI, Mucida D, Kappes DJ. Basu J, et al. Among authors: ferchen k. Nat Immunol. 2021 Aug;22(8):969-982. doi: 10.1038/s41590-021-00980-8. Epub 2021 Jul 26. Nat Immunol. 2021. PMID: 34312548 Free PMC article.
ThPOK is a critical multifaceted regulator of myeloid lineage development.
Basu J, Olsson A, Ferchen K, Titerina EK, Chetal K, Nicolas E, Czyzewicz P, Levchenko D, Ge L, Hua X, Grimes HL, Salomonis N, Kappes DJ. Basu J, et al. Among authors: ferchen k. Nat Immunol. 2023 Aug;24(8):1295-1307. doi: 10.1038/s41590-023-01549-3. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474652 Free PMC article.
A primer on single-cell genomics in myeloid biology.
Ferchen K, Song B, Leighton Grimes H. Ferchen K, et al. Curr Opin Hematol. 2021 Jan;28(1):11-17. doi: 10.1097/MOH.0000000000000623. Curr Opin Hematol. 2021. PMID: 33186153 Free PMC article. Review.
Author Correction: Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia.
Jiang X, Hu C, Ferchen K, Nie J, Cui X, Chen CH, Cheng L, Zuo Z, Seibel W, He C, Tang Y, Skibbe JR, Wunderlich M, Reinhold WC, Dong L, Shen C, Arnovitz S, Ulrich B, Lu J, Weng H, Su R, Huang H, Wang Y, Li C, Qin X, Mulloy JC, Zheng Y, Diao J, Jin J, Li C, Liu PP, He C, Chen Y, Chen J. Jiang X, et al. Among authors: ferchen k. Nat Commun. 2018 Feb 9;9(1):670. doi: 10.1038/s41467-018-02947-0. Nat Commun. 2018. PMID: 29426862 Free PMC article.
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC.
Li C, Dong L, Su R, Bi Y, Qing Y, Deng X, Zhou Y, Hu C, Yu M, Huang H, Jiang X, Li X, He X, Zou D, Shen C, Han L, Sun M, Skibbe J, Ferchen K, Qin X, Weng H, Huang H, Song C, Chen J, Jin J. Li C, et al. Among authors: ferchen k. Haematologica. 2020 Jan;105(1):148-160. doi: 10.3324/haematol.2018.208835. Epub 2019 Apr 11. Haematologica. 2020. PMID: 30975912 Free PMC article.
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