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Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform.
Olsen A, Harpaz Z, Ren C, Shneyderman A, Veviorskiy A, Dralkina M, Konnov S, Shcheglova O, Pun FW, Leung GHD, Leung HW, Ozerov IV, Aliper A, Korzinkin M, Zhavoronkov A. Olsen A, et al. Among authors: ozerov iv. Aging (Albany NY). 2023 Apr 26;15(8):2863-2876. doi: 10.18632/aging.204678. Epub 2023 Apr 26. Aging (Albany NY). 2023. PMID: 37100462 Free PMC article.
Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells.
Pustovalova M, Grekhova A, Astrelina Т, Nikitina V, Dobrovolskaya E, Suchkova Y, Kobzeva I, Usupzhanova D, Vorobyeva N, Samoylov A, Bushmanov A, Ozerov IV, Zhavoronkov A, Leonov S, Klokov D, Osipov AN. Pustovalova M, et al. Among authors: ozerov iv. Aging (Albany NY). 2016 Dec 11;8(12):3498-3506. doi: 10.18632/aging.101142. Aging (Albany NY). 2016. PMID: 27959319 Free PMC article.
Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells.
Pustovalova M, Astrelina ТA, Grekhova A, Vorobyeva N, Tsvetkova A, Blokhina T, Nikitina V, Suchkova Y, Usupzhanova D, Brunchukov V, Kobzeva I, Karaseva Т, Ozerov IV, Samoylov A, Bushmanov A, Leonov S, Izumchenko E, Zhavoronkov A, Klokov D, Osipov AN. Pustovalova M, et al. Among authors: ozerov iv. Aging (Albany NY). 2017 Nov 21;9(11):2397-2410. doi: 10.18632/aging.101327. Aging (Albany NY). 2017. PMID: 29165316 Free PMC article.
Aging and drug discovery.
Bakula D, Aliper AM, Mamoshina P, Petr MA, Teklu A, Baur JA, Campisi J, Ewald CY, Georgievskaya A, Gladyshev VN, Kovalchuk O, Lamming DW, Luijsterburg MS, Martín-Montalvo A, Maudsley S, Mkrtchyan GV, Moskalev A, Olshansky SJ, Ozerov IV, Pickett A, Ristow M, Zhavoronkov A, Scheibye-Knudsen M. Bakula D, et al. Among authors: ozerov iv. Aging (Albany NY). 2018 Nov 13;10(11):3079-3088. doi: 10.18632/aging.101646. Aging (Albany NY). 2018. PMID: 30425188 Free PMC article.
PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40).
Subbannayya T, Leal-Rojas P, Zhavoronkov A, Ozerov IV, Korzinkin M, Babu N, Radhakrishnan A, Chavan S, Raja R, Pinto SM, Patil AH, Barbhuiya MA, Kumar P, Guerrero-Preston R, Navani S, Tiwari PK, Kumar RV, Prasad TSK, Roa JC, Pandey A, Sidransky D, Gowda H, Izumchenko E, Chatterjee A. Subbannayya T, et al. Among authors: ozerov iv. J Cell Commun Signal. 2019 Jun;13(2):163-177. doi: 10.1007/s12079-018-00503-5. Epub 2019 Jan 21. J Cell Commun Signal. 2019. PMID: 30666556 Free PMC article.
Latest advances in aging research and drug discovery.
Bakula D, Ablasser A, Aguzzi A, Antebi A, Barzilai N, Bittner MI, Jensen MB, Calkhoven CF, Chen D, Grey ADNJ, Feige JN, Georgievskaya A, Gladyshev VN, Golato T, Gudkov AV, Hoppe T, Kaeberlein M, Katajisto P, Kennedy BK, Lal U, Martin-Villalba A, Moskalev AA, Ozerov I, Petr MA, Reason, Rubinsztein DC, Tyshkovskiy A, Vanhaelen Q, Zhavoronkov A, Scheibye-Knudsen M. Bakula D, et al. Aging (Albany NY). 2019 Nov 21;11(22):9971-9981. doi: 10.18632/aging.102487. Epub 2019 Nov 21. Aging (Albany NY). 2019. PMID: 31770722 Free PMC article.
Radioprotectors.org: an open database of known and predicted radioprotectors.
Aliper AM, Bozdaganyan ME, Sarkisova VA, Veviorsky AP, Ozerov IV, Orekhov PS, Korzinkin MB, Moskalev A, Zhavoronkov A, Osipov AN. Aliper AM, et al. Among authors: ozerov iv. Aging (Albany NY). 2020 Aug 15;12(15):15741-15755. doi: 10.18632/aging.103815. Epub 2020 Aug 15. Aging (Albany NY). 2020. PMID: 32805729 Free PMC article.
COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity.
Naumov V, Putin E, Pushkov S, Kozlova E, Romantsov K, Kalashnikov A, Galkin F, Tihonova N, Shneyderman A, Galkin E, Zinkevich A, Cope SM, Sethuraman R, Oprea TI, Pearson AT, Tay S, Agrawal N, Dubovenko A, Vanhaelen Q, Ozerov I, Aliper A, Izumchenko E, Zhavoronkov A. Naumov V, et al. PLoS Comput Biol. 2021 Jul 14;17(7):e1009183. doi: 10.1371/journal.pcbi.1009183. eCollection 2021 Jul. PLoS Comput Biol. 2021. PMID: 34260589 Free PMC article.
Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma.
Broner EC, Trujillo JA, Korzinkin M, Subbannayya T, Agrawal N, Ozerov IV, Zhavoronkov A, Rooper L, Kotlov N, Shen L, Pearson AT, Rosenberg AJ, Savage PA, Mishra V, Chatterjee A, Sidransky D, Izumchenko E. Broner EC, et al. Among authors: ozerov iv. Front Oncol. 2021 Jul 16;11:677051. doi: 10.3389/fonc.2021.677051. eCollection 2021. Front Oncol. 2021. PMID: 34336664 Free PMC article.
39 results