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Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions.
Papa A, Pasquini S, Galvani F, Cammarota M, Contri C, Carullo G, Gemma S, Ramunno A, Lamponi S, Gorelli B, Saponara S, Varani K, Mor M, Campiani G, Boscia F, Vincenzi F, Lodola A, Butini S. Papa A, et al. Among authors: vincenzi f. Eur J Med Chem. 2023 Jan 15;246:114952. doi: 10.1016/j.ejmech.2022.114952. Epub 2022 Nov 25. Eur J Med Chem. 2023. PMID: 36462439
A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients.
Rossi S, Tatangelo V, Dichiara M, Butini S, Gemma S, Brogi S, Pasquini S, Cappello M, Vincenzi F, Varani K, Lopresti L, Malchiodi M, Carrara C, Gozzetti A, Bocchia M, Marotta G, Patrussi L, Carullo G, Baldari CT, Campiani G. Rossi S, et al. Among authors: vincenzi f. Biomed Pharmacother. 2024 May;174:116537. doi: 10.1016/j.biopha.2024.116537. Epub 2024 Apr 4. Biomed Pharmacother. 2024. PMID: 38579402 Free article.
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy.
Carullo G, Orsini N, Piano I, Pozzetti L, Papa A, Fontana A, Napoli D, Corsi F, Marco BD, Galante A, Marotta L, Panzeca G, O'Brien J, Sanchez AG, Doherty H, Mahon N, Clarke L, Contri C, Pasquini S, Gorelli B, Saponara S, Valoti M, Vincenzi F, Varani K, Ramunno A, Brogi S, Butini S, Gemma S, Kennedy BN, Gargini C, Strettoi E, Campiani G. Carullo G, et al. Among authors: vincenzi f. J Med Chem. 2024 Sep 12;67(17):14946-14973. doi: 10.1021/acs.jmedchem.4c00477. Epub 2024 Jul 4. J Med Chem. 2024. PMID: 38961727
Development of Epigenetic Modifiers with Therapeutic Potential in FMS-Related Tyrosine Kinase 3/Internal Tandem Duplication (FLT3/ITD) Acute Myeloid Leukemia and Other Blood Malignancies.
Carullo G, Rossi S, Giudice V, Pezzotta A, Chianese U, Scala P, Carbone S, Fontana A, Panzeca G, Pasquini S, Contri C, Gemma S, Ramunno A, Saponara S, Galvani F, Lodola A, Mor M, Benedetti R, Selleri C, Varani K, Butini S, Altucci L, Vincenzi F, Pistocchi A, Campiani G. Carullo G, et al. Among authors: vincenzi f. ACS Pharmacol Transl Sci. 2024 Jul 2;7(7):2125-2142. doi: 10.1021/acsptsci.4c00208. eCollection 2024 Jul 12. ACS Pharmacol Transl Sci. 2024. PMID: 39022363
MAM-2201 acute administration impairs motor, sensorimotor, prepulse inhibition, and memory functions in mice: a comparison with its analogue AM-2201.
Corli G, Tirri M, Bilel S, Arfè R, Coccini T, Roda E, Marchetti B, Vincenzi F, Zauli G, Borea PA, Locatelli CA, Varani K, Marti M. Corli G, et al. Among authors: vincenzi f. Psychopharmacology (Berl). 2023 Jul;240(7):1435-1452. doi: 10.1007/s00213-023-06378-8. Epub 2023 May 26. Psychopharmacology (Berl). 2023. PMID: 37233813 Free PMC article.
264 results