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Page 1
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia.
Laurila PP, Wohlwend M, Imamura de Lima T, Luan P, Herzig S, Zanou N, Crisol B, Bou-Sleiman M, Porcu E, Gallart-Ayala H, Handzlik MK, Wang Q, Jain S, D'Amico D, Salonen M, Metallo CM, Kutalik Z, Eichmann TO, Place N, Ivanisevic J, Lahti J, Eriksson JG, Auwerx J. Laurila PP, et al. Among authors: bou sleiman m. Nat Aging. 2022 Dec;2(12):1159-1175. doi: 10.1038/s43587-022-00309-6. Epub 2022 Dec 16. Nat Aging. 2022. PMID: 37118545
An Integrated Systems Genetics and Omics Toolkit to Probe Gene Function.
Li H, Wang X, Rukina D, Huang Q, Lin T, Sorrentino V, Zhang H, Bou Sleiman M, Arends D, McDaid A, Luan P, Ziari N, Velázquez-Villegas LA, Gariani K, Kutalik Z, Schoonjans K, Radcliffe RA, Prins P, Morgenthaler S, Williams RW, Auwerx J. Li H, et al. Cell Syst. 2018 Jan 24;6(1):90-102.e4. doi: 10.1016/j.cels.2017.10.016. Epub 2017 Nov 30. Cell Syst. 2018. PMID: 29199021 Free article.
Genetic cartography of longevity in humans and mice: Current landscape and horizons.
Hook M, Roy S, Williams EG, Bou Sleiman M, Mozhui K, Nelson JF, Lu L, Auwerx J, Williams RW. Hook M, et al. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt A):2718-2732. doi: 10.1016/j.bbadis.2018.01.026. Epub 2018 Feb 2. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 29410319 Free PMC article. Review.
Integrative systems analysis identifies genetic and dietary modulators of bile acid homeostasis.
Li H, Perino A, Huang Q, Von Alvensleben GVG, Banaei-Esfahani A, Velazquez-Villegas LA, Gariani K, Korbelius M, Bou Sleiman M, Imbach J, Sun Y, Li X, Bachmann A, Goeminne LJE, Gallart-Ayala H, Williams EG, Ivanisevic J, Auwerx J, Schoonjans K. Li H, et al. Among authors: bou sleiman m. Cell Metab. 2022 Oct 4;34(10):1594-1610.e4. doi: 10.1016/j.cmet.2022.08.015. Epub 2022 Sep 12. Cell Metab. 2022. PMID: 36099916 Free PMC article.
Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, Sen S, Harrison DE, Nelson JF, Strong R, Miller RA, Kutalik Z, Williams RW, Auwerx J. Bou Sleiman M, et al. Science. 2022 Sep 30;377(6614):eabo3191. doi: 10.1126/science.abo3191. Epub 2022 Sep 30. Science. 2022. PMID: 36173858 Free PMC article.
COX7A2L genetic variants determine cardiorespiratory fitness in mice and human.
Benegiamo G, Bou Sleiman M, Wohlwend M, Rodríguez-López S, Goeminne LJE, Laurila PP, Klevjer M, Salonen MK, Lahti J, Jha P, Cogliati S, Enriquez JA, Brumpton BM, Bye A, Eriksson JG, Auwerx J. Benegiamo G, et al. Among authors: bou sleiman m. Nat Metab. 2022 Oct;4(10):1336-1351. doi: 10.1038/s42255-022-00655-0. Epub 2022 Oct 17. Nat Metab. 2022. PMID: 36253618 Free PMC article.
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression.
Benegiamo G, von Alvensleben GVG, Rodríguez-López S, Goeminne LJE, Bachmann AM, Morel JD, Broeckx E, Ma JY, Carreira V, Youssef SA, Azhar N, Reilly DF, D'Aquino K, Mullican S, Bou-Sleiman M, Auwerx J. Benegiamo G, et al. Among authors: bou sleiman m. J Exp Med. 2023 Apr 3;220(4):e20221738. doi: 10.1084/jem.20221738. Epub 2023 Feb 14. J Exp Med. 2023. PMID: 36787127 Free PMC article.
22 results