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Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus.
Zepp JA, Morley MP, Loebel C, Kremp MM, Chaudhry FN, Basil MC, Leach JP, Liberti DC, Niethamer TK, Ying Y, Jayachandran S, Babu A, Zhou S, Frank DB, Burdick JA, Morrisey EE. Zepp JA, et al. Among authors: ying y. Science. 2021 Mar 12;371(6534):eabc3172. doi: 10.1126/science.abc3172. Science. 2021. PMID: 33707239 Free PMC article.
Human distal airways contain a multipotent secretory cell that can regenerate alveoli.
Basil MC, Cardenas-Diaz FL, Kathiriya JJ, Morley MP, Carl J, Brumwell AN, Katzen J, Slovik KJ, Babu A, Zhou S, Kremp MM, McCauley KB, Li S, Planer JD, Hussain SS, Liu X, Windmueller R, Ying Y, Stewart KM, Oyster M, Christie JD, Diamond JM, Engelhardt JF, Cantu E, Rowe SM, Kotton DN, Chapman HA, Morrisey EE. Basil MC, et al. Among authors: ying y. Nature. 2022 Apr;604(7904):120-126. doi: 10.1038/s41586-022-04552-0. Epub 2022 Mar 30. Nature. 2022. PMID: 35355013 Free PMC article.
Guided construction of single cell reference for human and mouse lung.
Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, Zhao S, Wagner A, Cakar AC, Kouril M, Jin K, Gaddis N, Kitzmiller JA, Stewart K, Basil MC, Lin SM, Ying Y, Babu A, Wikenheiser-Brokamp KA, Mun KS, Naren AP, Clair G, Adkins JN, Pryhuber GS, Misra RS, Aronow BJ, Tickle TL, Salomonis N, Sun X, Morrisey EE, Whitsett JA; NHLBI LungMAP Consortium; Xu Y. Guo M, et al. Among authors: ying y. Nat Commun. 2023 Jul 29;14(1):4566. doi: 10.1038/s41467-023-40173-5. Nat Commun. 2023. PMID: 37516747 Free PMC article.
An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung.
Jones DL, Morley MP, Li X, Ying Y, Cardenas-Diaz FL, Li S, Zhou S, Schaefer SE, Chembazhi UV, Nottingham A, Lin S, Cantu E, Diamond JM, Basil MC, Vaughan AE, Morrisey EE. Jones DL, et al. Among authors: ying y. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582147. doi: 10.1101/2024.02.26.582147. bioRxiv. 2024. PMID: 38529490 Free PMC article. Preprint.
2,065 results