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Epigenetic reprogramming of cancer cells via targeted DNA methylation.
Rivenbark AG, Stolzenburg S, Beltran AS, Yuan X, Rots MG, Strahl BD, Blancafort P. Rivenbark AG, et al. Among authors: blancafort p. Epigenetics. 2012 Apr;7(4):350-60. doi: 10.4161/epi.19507. Epub 2012 Apr 1. Epigenetics. 2012. PMID: 22419067 Free PMC article.
Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system.
Garcia-Bloj B, Moses C, Sgro A, Plani-Lam J, Arooj M, Duffy C, Thiruvengadam S, Sorolla A, Rashwan R, Mancera RL, Leisewitz A, Swift-Scanlan T, Corvalan AH, Blancafort P. Garcia-Bloj B, et al. Among authors: blancafort p. Oncotarget. 2016 Sep 13;7(37):60535-60554. doi: 10.18632/oncotarget.11142. Oncotarget. 2016. PMID: 27528034 Free PMC article.
Activating PTEN Tumor Suppressor Expression with the CRISPR/dCas9 System.
Moses C, Nugent F, Waryah CB, Garcia-Bloj B, Harvey AR, Blancafort P. Moses C, et al. Among authors: blancafort p. Mol Ther Nucleic Acids. 2019 Mar 1;14:287-300. doi: 10.1016/j.omtn.2018.12.003. Epub 2018 Dec 14. Mol Ther Nucleic Acids. 2019. PMID: 30654190 Free PMC article.
Tumour suppression by targeted intravenous non-viral CRISPRa using dendritic polymers.
Kretzmann JA, Evans CW, Moses C, Sorolla A, Kretzmann AL, Wang E, Ho D, Hackett MJ, Dessauvagie BF, Smith NM, Redfern AD, Waryah C, Norret M, Iyer KS, Blancafort P. Kretzmann JA, et al. Among authors: blancafort p. Chem Sci. 2019 Jun 27;10(33):7718-7727. doi: 10.1039/c9sc01432b. eCollection 2019 Sep 7. Chem Sci. 2019. PMID: 31588320 Free PMC article.
67 results