Lyu R - Search Results

1

Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma.

Sgro A, Cursons J, Waryah C, Woodward EA, Foroutan M, Lyu R, Yeoh GCT, Leedman PJ, Blancafort P. Sgro A, et al. Among authors: lyu r. Clin Epigenetics. 2023 Apr 29;15(1):73. doi: 10.1186/s13148-023-01482-0. Clin Epigenetics. 2023. PMID: 37120619 Free PMC article.

2

Single sample scoring of molecular phenotypes.

Foroutan M, Bhuva DD, Lyu R, Horan K, Cursons J, Davis MJ. Foroutan M, et al. Among authors: lyu r. BMC Bioinformatics. 2018 Nov 6;19(1):404. doi: 10.1186/s12859-018-2435-4. BMC Bioinformatics. 2018. PMID: 30400809 Free PMC article.

3

Using singscore to predict mutation status in acute myeloid leukemia from transcriptomic signatures.

Bhuva DD, Foroutan M, Xie Y, Lyu R, Cursons J, Davis MJ. Bhuva DD, et al. Among authors: lyu r. F1000Res. 2019 Jun 3;8:776. doi: 10.12688/f1000research.19236.3. eCollection 2019. F1000Res. 2019. PMID: 31723419 Free PMC article.

4

sgcocaller and comapr: personalised haplotype assembly and comparative crossover map analysis using single-gamete sequencing data.

Lyu R, Tsui V, Crismani W, Liu R, Shim H, McCarthy DJ. Lyu R, et al. Nucleic Acids Res. 2022 Nov 11;50(20):e118. doi: 10.1093/nar/gkac764. Nucleic Acids Res. 2022. PMID: 36107768 Free PMC article.

5

Fancm has dual roles in the limiting of meiotic crossovers and germ cell maintenance in mammals.

Tsui V, Lyu R, Novakovic S, Stringer JM, Dunleavy JEM, Granger E, Semple T, Leichter A, Martelotto LG, Merriner DJ, Liu R, McNeill L, Zerafa N, Hoffmann ER, O'Bryan MK, Hutt K, Deans AJ, Heierhorst J, McCarthy DJ, Crismani W. Tsui V, et al. Among authors: lyu r. Cell Genom. 2023 Jun 29;3(8):100349. doi: 10.1016/j.xgen.2023.100349. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601968 Free PMC article.

6

Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema.

Ishaq M, Bandara N, Morgan S, Nowell C, Mehdi AM, Lyu R, McCarthy D, Anderson D, Creek DJ, Achen MG, Shayan R, Karnezis T. Ishaq M, et al. Among authors: lyu r. Int J Obes (Lond). 2022 Mar;46(3):502-514. doi: 10.1038/s41366-021-01002-1. Epub 2021 Nov 11. Int J Obes (Lond). 2022. PMID: 34764426 Free PMC article.

7

Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult - a Molecular Approach.

Koneshamoorthy A, Seniveratne-Epa D, Calder G, Sawyer M, Kay TWH, Farrell S, Loudovaris T, Mariana L, McCarthy D, Lyu R, Liu X, Thorn P, Tong J, Chin LK, Zacharin M, Trainer A, Taylor S, MacIsaac RJ, Sachithanandan N, Thomas HE, Krishnamurthy B. Koneshamoorthy A, et al. Among authors: lyu r. Front Endocrinol (Lausanne). 2022 Mar 17;13:842937. doi: 10.3389/fendo.2022.842937. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35370948 Free PMC article.

8

Personalized genome structure via single gamete sequencing.

Lyu R, Tsui V, McCarthy DJ, Crismani W. Lyu R, et al. Genome Biol. 2021 Apr 19;22(1):112. doi: 10.1186/s13059-021-02327-w. Genome Biol. 2021. PMID: 33874978 Free PMC article. Review.

9

Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes.

McCarthy DJ, Rostom R, Huang Y, Kunz DJ, Danecek P, Bonder MJ, Hagai T, Lyu R; HipSci Consortium; Wang W, Gaffney DJ, Simons BD, Stegle O, Teichmann SA. McCarthy DJ, et al. Among authors: lyu r. Nat Methods. 2020 Apr;17(4):414-421. doi: 10.1038/s41592-020-0766-3. Epub 2020 Mar 16. Nat Methods. 2020. PMID: 32203388

10

Transcriptional Reprogramming Deploys a Compartmentalized 'Timebomb' in Catharanthus roseus to Fend Off Chewing Herbivores.

Liu Y, Shi J, Patra B, Singh SK, Wu X, Lyu R, Liu X, Li Y, Wang Y, Zhou X, Pattanaik S, Yuan L. Liu Y, et al. Among authors: lyu r. Plant Cell Environ. 2024 Dec 24. doi: 10.1111/pce.15324. Online ahead of print. Plant Cell Environ. 2024. PMID: 39718032

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