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IL-8 concurrently promotes idiopathic pulmonary fibrosis mesenchymal progenitor cell senescence and PD-L1 expression enabling escape from immune cell surveillance.
Yang L, Xia H, Gilbertsen A, Smith K, Racila E, Bitterman PB, Henke CA. Yang L, et al. Among authors: smith k. Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1;324(6):L849-L862. doi: 10.1152/ajplung.00028.2023. Epub 2023 Apr 25. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37121574 Free PMC article.
Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors.
Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, Bitterman PB, Polunovsky VA. Larsson O, et al. Among authors: smith k. Cancer Res. 2007 Jul 15;67(14):6814-24. doi: 10.1158/0008-5472.CAN-07-0752. Cancer Res. 2007. PMID: 17638893
Fibrotic extracellular matrix activates a profibrotic positive feedback loop.
Parker MW, Rossi D, Peterson M, Smith K, Sikström K, White ES, Connett JE, Henke CA, Larsson O, Bitterman PB. Parker MW, et al. Among authors: smith k. J Clin Invest. 2014 Apr;124(4):1622-35. doi: 10.1172/JCI71386. Epub 2014 Mar 3. J Clin Invest. 2014. PMID: 24590289 Free PMC article.
Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis.
Xia H, Bodempudi V, Benyumov A, Hergert P, Tank D, Herrera J, Braziunas J, Larsson O, Parker M, Rossi D, Smith K, Peterson M, Limper A, Jessurun J, Connett J, Ingbar D, Phan S, Bitterman PB, Henke CA. Xia H, et al. Among authors: smith k. Am J Pathol. 2014 May;184(5):1369-83. doi: 10.1016/j.ajpath.2014.01.012. Epub 2014 Mar 13. Am J Pathol. 2014. PMID: 24631025 Free PMC article.
miR-210 promotes IPF fibroblast proliferation in response to hypoxia.
Bodempudi V, Hergert P, Smith K, Xia H, Herrera J, Peterson M, Khalil W, Kahm J, Bitterman PB, Henke CA. Bodempudi V, et al. Among authors: smith k. Am J Physiol Lung Cell Mol Physiol. 2014 Aug 15;307(4):L283-94. doi: 10.1152/ajplung.00069.2014. Epub 2014 Jun 20. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 24951777 Free PMC article.
eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells.
Avdulov S, Herrera J, Smith K, Peterson M, Gomez-Garcia JR, Beadnell TC, Schwertfeger KL, Benyumov AO, Manivel JC, Li S, Bielinsky AK, Yee D, Bitterman PB, Polunovsky VA. Avdulov S, et al. Among authors: smith k. Cancer Res. 2015 Feb 15;75(4):687-97. doi: 10.1158/0008-5472.CAN-14-2571. Epub 2014 Dec 18. Cancer Res. 2015. PMID: 25524901 Free PMC article.
Pathologic Regulation of Collagen I by an Aberrant Protein Phosphatase 2A/Histone Deacetylase C4/MicroRNA-29 Signal Axis in Idiopathic Pulmonary Fibrosis Fibroblasts.
Khalil W, Xia H, Bodempudi V, Kahm J, Hergert P, Smith K, Peterson M, Parker M, Herrera J, Bitterman PB, Henke CA. Khalil W, et al. Among authors: smith k. Am J Respir Cell Mol Biol. 2015 Sep;53(3):391-9. doi: 10.1165/rcmb.2014-0150OC. Am J Respir Cell Mol Biol. 2015. PMID: 25612003 Free PMC article.
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