Tuttle KS - Search Results

1

Altered receptor binding, antibody evasion and retention of T cell recognition by the SARS-CoV-2 XBB.1.5 spike protein.

Mannar D, Saville JW, Poloni C, Zhu X, Bezeruk A, Tidey K, Ahmed S, Tuttle KS, Vahdatihassani F, Cholak S, Cook L, Steiner TS, Subramaniam S. Mannar D, et al. Among authors: tuttle ks. Nat Commun. 2024 Feb 29;15(1):1854. doi: 10.1038/s41467-024-46104-2. Nat Commun. 2024. PMID: 38424106 Free PMC article.

2

Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.

Cholak S, Saville JW, Zhu X, Berezuk AM, Tuttle KS, Haji-Ghassemi O, Alvarado FJ, Van Petegem F, Subramaniam S. Cholak S, et al. Among authors: tuttle ks. Structure. 2023 Jul 6;31(7):790-800.e4. doi: 10.1016/j.str.2023.04.009. Epub 2023 May 15. Structure. 2023. PMID: 37192614 Free PMC article.

3

Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer.

Wall SW, Sanchez L, Tuttle KS, Pearson SJ, Soma S, Wyatt GL, Carter HN, Jenschke RM, Tan L, Martinez SA, Lorenzi PL, Gohil VM, Rijnkels M, Porter WW. Wall SW, et al. Among authors: tuttle ks. Exp Mol Med. 2023 May;55(5):1046-1063. doi: 10.1038/s12276-023-00996-0. Epub 2023 May 1. Exp Mol Med. 2023. PMID: 37121978 Free PMC article.

4

Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein.

Saville JW, Mannar D, Zhu X, Berezuk AM, Cholak S, Tuttle KS, Vahdatihassani F, Subramaniam S. Saville JW, et al. Among authors: tuttle ks. Cell Rep. 2023 Jan 31;42(1):111964. doi: 10.1016/j.celrep.2022.111964. Epub 2023 Jan 4. Cell Rep. 2023. PMID: 36640338 Free PMC article.

5

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization.

Mannar D, Saville JW, Sun Z, Zhu X, Marti MM, Srivastava SS, Berezuk AM, Zhou S, Tuttle KS, Sobolewski MD, Kim A, Treat BR, Da Silva Castanha PM, Jacobs JL, Barratt-Boyes SM, Mellors JW, Dimitrov DS, Li W, Subramaniam S. Mannar D, et al. Among authors: tuttle ks. Nat Commun. 2022 Aug 18;13(1):4696. doi: 10.1038/s41467-022-32262-8. Nat Commun. 2022. PMID: 35982054 Free PMC article.

6

Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants.

Saville JW, Mannar D, Zhu X, Srivastava SS, Berezuk AM, Demers JP, Zhou S, Tuttle KS, Sekirov I, Kim A, Li W, Dimitrov DS, Subramaniam S. Saville JW, et al. Among authors: tuttle ks. Nat Commun. 2022 Feb 8;13(1):742. doi: 10.1038/s41467-022-28324-6. Nat Commun. 2022. PMID: 35136050 Free PMC article.

7

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex.

Mannar D, Saville JW, Zhu X, Srivastava SS, Berezuk AM, Tuttle KS, Marquez AC, Sekirov I, Subramaniam S. Mannar D, et al. Among authors: tuttle ks. Science. 2022 Feb 18;375(6582):760-764. doi: 10.1126/science.abn7760. Epub 2022 Jan 20. Science. 2022. PMID: 35050643 Free PMC article.

8

Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding.

Mannar D, Saville JW, Zhu X, Srivastava SS, Berezuk AM, Zhou S, Tuttle KS, Kim A, Li W, Dimitrov DS, Subramaniam S. Mannar D, et al. Among authors: tuttle ks. Cell Rep. 2021 Dec 21;37(12):110156. doi: 10.1016/j.celrep.2021.110156. Epub 2021 Dec 4. Cell Rep. 2021. PMID: 34914928 Free PMC article.

9

Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.

Zhu X, Mannar D, Srivastava SS, Berezuk AM, Demers JP, Saville JW, Leopold K, Li W, Dimitrov DS, Tuttle KS, Zhou S, Chittori S, Subramaniam S. Zhu X, et al. Among authors: tuttle ks. PLoS Biol. 2021 Apr 29;19(4):e3001237. doi: 10.1371/journal.pbio.3001237. eCollection 2021 Apr. PLoS Biol. 2021. PMID: 33914735 Free PMC article.

10

ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms.

Sheynkman GM, Tuttle KS, Laval F, Tseng E, Underwood JG, Yu L, Dong D, Smith ML, Sebra R, Willems L, Hao T, Calderwood MA, Hill DE, Vidal M. Sheynkman GM, et al. Among authors: tuttle ks. Nat Commun. 2020 May 11;11(1):2326. doi: 10.1038/s41467-020-16174-z. Nat Commun. 2020. PMID: 32393825 Free PMC article.

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