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nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome.
Dagher M, Ongo G, Robichaud N, Kong J, Rho W, Teahulos I, Tavakoli A, Bovaird S, Merjaneh S, Tan A, Edwardson K, Scheepers C, Ng A, Hajjar A, Sow B, Vrouvides M, Lee A, DeCorwin-Martin P, Rasool S, Huang J, Han Y, Erps T, Coffin S, Chandrasekaran SN, Miller L, Kost-Alimova M, Skepner A, Singh S, Carpenter AE, Munzar J, Juncker D. Dagher M, et al. Among authors: carpenter ae. bioRxiv [Preprint]. 2023 Jun 28:2023.04.17.535914. doi: 10.1101/2023.04.17.535914. bioRxiv. 2023. PMID: 37131604 Free PMC article. Preprint.
Applications in image-based profiling of perturbations.
Caicedo JC, Singh S, Carpenter AE. Caicedo JC, et al. Among authors: carpenter ae. Curr Opin Biotechnol. 2016 Jun;39:134-142. doi: 10.1016/j.copbio.2016.04.003. Epub 2016 Apr 17. Curr Opin Biotechnol. 2016. PMID: 27089218 Free article. Review.
Image-based profiling for drug discovery: due for a machine-learning upgrade?
Chandrasekaran SN, Ceulemans H, Boyd JD, Carpenter AE. Chandrasekaran SN, et al. Among authors: carpenter ae. Nat Rev Drug Discov. 2021 Feb;20(2):145-159. doi: 10.1038/s41573-020-00117-w. Epub 2020 Dec 22. Nat Rev Drug Discov. 2021. PMID: 33353986 Free PMC article. Review.
Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations.
Chandrasekaran SN, Cimini BA, Goodale A, Miller L, Kost-Alimova M, Jamali N, Doench JG, Fritchman B, Skepner A, Melanson M, Kalinin AA, Arevalo J, Haghighi M, Caicedo JC, Kuhn D, Hernandez D, Berstler J, Shafqat-Abbasi H, Root DE, Swalley SE, Garg S, Singh S, Carpenter AE. Chandrasekaran SN, et al. Among authors: carpenter ae. Nat Methods. 2024 Jun;21(6):1114-1121. doi: 10.1038/s41592-024-02241-6. Epub 2024 Apr 9. Nat Methods. 2024. PMID: 38594452 Free PMC article.
Capturing cell heterogeneity in representations of cell populations for image-based profiling using contrastive learning.
van Dijk R, Arevalo J, Babadi M, Carpenter AE, Singh S. van Dijk R, et al. Among authors: carpenter ae. bioRxiv [Preprint]. 2024 Jul 31:2023.11.14.567038. doi: 10.1101/2023.11.14.567038. bioRxiv. 2024. Update in: PLoS Comput Biol. 2024 Nov 11;20(11):e1012547. doi: 10.1371/journal.pcbi.1012547 PMID: 39131344 Free PMC article. Updated. Preprint.
213 results