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Page 1
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial.
Park HS, Yin A, Barranta C, Lee JS, Caputo CA, Sachithanandham J, Li M, Yoon S, Sitaras I, Jedlicka A, Eby Y, Ram M, Fernandez RE, Baker OR, Shenoy AG, Mosnaim GS, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Gerber JM, Petrini JR, Broderick PB, Rausch W, Cordisco ME, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Raval JS, Kassaye SG, Marshall CE, Yarava A, Lane K, McBee NA, Gawad AL, Karlen N, Singh A, Ford DE, Jabs DA, Appel LJ, Shade DM, Lau B, Ehrhardt S, Baksh SN, Shapiro JR, Ou J, Na YB, Knoll MD, Ornelas-Gatdula E, Arroyo-Curras N, Gniadek TJ, Caturegli P, Wu J, Ndahiro N, Betenbaugh MJ, Ziman A, Hanley DF, Casadevall A, Shoham S, Bloch EM, Gebo KA, Tobian AAR, Laeyendecker O, Pekosz A, Klein SL, Sullivan DJ. Park HS, et al. Among authors: sullivan dj. medRxiv [Preprint]. 2023 Dec 15:2023.04.13.23288353. doi: 10.1101/2023.04.13.23288353. medRxiv. 2023. Update in: JCI Insight. 2024 Mar 14;9(8):e178460. doi: 10.1172/jci.insight.178460 PMID: 37131659 Free PMC article. Updated. Preprint.
Deployment of convalescent plasma for the prevention and treatment of COVID-19.
Bloch EM, Shoham S, Casadevall A, Sachais BS, Shaz B, Winters JL, van Buskirk C, Grossman BJ, Joyner M, Henderson JP, Pekosz A, Lau B, Wesolowski A, Katz L, Shan H, Auwaerter PG, Thomas D, Sullivan DJ, Paneth N, Gehrie E, Spitalnik S, Hod EA, Pollack L, Nicholson WT, Pirofski LA, Bailey JA, Tobian AA. Bloch EM, et al. Among authors: sullivan dj. J Clin Invest. 2020 Jun 1;130(6):2757-2765. doi: 10.1172/JCI138745. J Clin Invest. 2020. PMID: 32254064 Free PMC article. Review.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein S, Pekosz A, Park HS, Ursin R, Shapiro J, Benner S, Littlefield K, Kumar S, Naik HM, Betenbaugh M, Shrestha R, Wu A, Hughes R, Burgess I, Caturegli P, Laeyendecker O, Quinn T, Sullivan D, Shoham S, Redd A, Bloch E, Casadevall A, Tobian A. Klein S, et al. medRxiv [Preprint]. 2020 Jun 28:2020.06.26.20139063. doi: 10.1101/2020.06.26.20139063. medRxiv. 2020. Update in: J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004 PMID: 32607519 Free PMC article. Updated. Preprint.
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population.
Klein SL, Pekosz A, Park HS, Ursin RL, Shapiro JR, Benner SE, Littlefield K, Kumar S, Naik HM, Betenbaugh MJ, Shrestha R, Wu AA, Hughes RM, Burgess I, Caturegli P, Laeyendecker O, Quinn TC, Sullivan D, Shoham S, Redd AD, Bloch EM, Casadevall A, Tobian AA. Klein SL, et al. J Clin Invest. 2020 Nov 2;130(11):6141-6150. doi: 10.1172/JCI142004. J Clin Invest. 2020. PMID: 32764200 Free PMC article.
Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. medRxiv [Preprint]. 2020 Sep 2:2020.08.31.20184788. doi: 10.1101/2020.08.31.20184788. medRxiv. 2020. Update in: J Clin Microbiol. 2021 Jan 21;59(2):e02257-20. doi: 10.1128/JCM.02257-20 PMID: 32908987 Free PMC article. Updated. Preprint.
SARS-CoV-2 Antibody Avidity Responses in COVID-19 Patients and Convalescent Plasma Donors.
Benner SE, Patel EU, Laeyendecker O, Pekosz A, Littlefield K, Eby Y, Fernandez RE, Miller J, Kirby CS, Keruly M, Klock E, Baker OR, Schmidt HA, Shrestha R, Burgess I, Bonny TS, Clarke W, Caturegli P, Sullivan D, Shoham S, Quinn TC, Bloch EM, Casadevall A, Tobian AAR, Redd AD. Benner SE, et al. J Infect Dis. 2020 Nov 13;222(12):1974-1984. doi: 10.1093/infdis/jiaa581. J Infect Dis. 2020. PMID: 32910175 Free PMC article.
SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy.
Natarajan H, Crowley AR, Butler SE, Xu S, Weiner JA, Bloch EM, Littlefield K, Wieland-Alter W, Connor RI, Wright PF, Benner SE, Bonny TS, Laeyendecker O, Sullivan D, Shoham S, Quinn TC, Larman HB, Casadevall A, Pekosz A, Redd AD, Tobian AAR, Ackerman ME. Natarajan H, et al. medRxiv [Preprint]. 2020 Sep 18:2020.09.16.20196154. doi: 10.1101/2020.09.16.20196154. medRxiv. 2020. PMID: 32995801 Free PMC article. Updated. Preprint.
CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation.
Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC. Kared H, et al. bioRxiv [Preprint]. 2020 Oct 8:2020.10.08.330688. doi: 10.1101/2020.10.08.330688. bioRxiv. 2020. PMID: 33052343 Free PMC article. Preprint.
Comparative Performance of Five Commercially Available Serologic Assays To Detect Antibodies to SARS-CoV-2 and Identify Individuals with High Neutralizing Titers.
Patel EU, Bloch EM, Clarke W, Hsieh YH, Boon D, Eby Y, Fernandez RE, Baker OR, Keruly M, Kirby CS, Klock E, Littlefield K, Miller J, Schmidt HA, Sullivan P, Piwowar-Manning E, Shrestha R, Redd AD, Rothman RE, Sullivan D, Shoham S, Casadevall A, Quinn TC, Pekosz A, Tobian AAR, Laeyendecker O. Patel EU, et al. J Clin Microbiol. 2021 Jan 21;59(2):e02257-20. doi: 10.1128/JCM.02257-20. Print 2021 Jan 21. J Clin Microbiol. 2021. PMID: 33139419 Free PMC article.
Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Morgenlander W, Henson S, Monaco D, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Ashwin Balagopal, Sullivan D, Shoham S, Quinn TC, Eshleman S, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AAR, Larman HB. Morgenlander W, et al. medRxiv [Preprint]. 2020 Dec 18:2020.12.16.20248294. doi: 10.1101/2020.12.16.20248294. medRxiv. 2020. Update in: J Clin Invest. 2021 Apr 1;131(7):146927. doi: 10.1172/JCI146927 PMID: 33354688 Free PMC article. Updated. Preprint.
324 results