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The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease.
Belcher JD, Nataraja S, Abdulla F, Zhang P, Chen C, Nguyen J, Ruan C, Singh M, Demes S, Olson L, Stickens D, Stanwix J, Clarke E, Huang Y, Biddle M, Vercellotti GM. Belcher JD, et al. Among authors: demes s. Front Med (Lausanne). 2023 Apr 18;10:1101501. doi: 10.3389/fmed.2023.1101501. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37144034 Free PMC article.