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Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation.
Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, Blair LJ. Hill SE, et al. Among authors: dickey ca. ACS Chem Biol. 2023 May 19;18(5):1124-1135. doi: 10.1021/acschembio.2c00919. Epub 2023 May 5. ACS Chem Biol. 2023. PMID: 37144894 Free PMC article.
Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ. Sabbagh JJ, et al. Among authors: dickey ca. ACS Chem Biol. 2018 Aug 17;13(8):2288-2299. doi: 10.1021/acschembio.8b00454. Epub 2018 Jun 19. ACS Chem Biol. 2018. PMID: 29893552 Free PMC article.
Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease.
Blair LJ, Sabbagh JJ, Dickey CA. Blair LJ, et al. Among authors: dickey ca. Expert Opin Ther Targets. 2014 Oct;18(10):1219-32. doi: 10.1517/14728222.2014.943185. Epub 2014 Jul 29. Expert Opin Ther Targets. 2014. PMID: 25069659 Free PMC article. Review.
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Martin MD, et al. Among authors: dickey ca. ACS Chem Biol. 2015 Apr 17;10(4):1099-109. doi: 10.1021/cb501013w. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25588114 Free PMC article.
Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels.
Webster JM, Darling AL, Sanders TA, Blazier DM, Vidal-Aguiar Y, Beaulieu-Abdelahad D, Plemmons DG, Hill SE, Uversky VN, Bickford PC, Dickey CA, Blair LJ. Webster JM, et al. Among authors: dickey ca. Int J Mol Sci. 2020 Jul 30;21(15):5442. doi: 10.3390/ijms21155442. Int J Mol Sci. 2020. PMID: 32751642 Free PMC article.
134 results