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Small molecule glucagon release inhibitors with activity in human islets.
Kalwat MA, Rodrigues-Dos-Santos K, Binns DD, Wei S, Zhou A, Evans MR, Posner BA, Roth MG, Cobb MH. Kalwat MA, et al. Among authors: roth mg. Front Endocrinol (Lausanne). 2023 Apr 19;14:1114799. doi: 10.3389/fendo.2023.1114799. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37152965 Free PMC article.
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Among authors: roth mg. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.
Targeting QseC signaling and virulence for antibiotic development.
Rasko DA, Moreira CG, Li de R, Reading NC, Ritchie JM, Waldor MK, Williams N, Taussig R, Wei S, Roth M, Hughes DT, Huntley JF, Fina MW, Falck JR, Sperandio V. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80. doi: 10.1126/science.1160354. Science. 2008. PMID: 18719281 Free PMC article.
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor.
Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM. Mata MA, et al. Among authors: roth mg. Nat Chem Biol. 2011 Sep 11;7(10):712-9. doi: 10.1038/nchembio.645. Nat Chem Biol. 2011. PMID: 21909097 Free PMC article.
XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer.
Kim J, McMillan E, Kim HS, Venkateswaran N, Makkar G, Rodriguez-Canales J, Villalobos P, Neggers JE, Mendiratta S, Wei S, Landesman Y, Senapedis W, Baloglu E, Chow CB, Frink RE, Gao B, Roth M, Minna JD, Daelemans D, Wistuba II, Posner BA, Scaglioni PP, White MA. Kim J, et al. Nature. 2016 Oct 6;538(7623):114-117. doi: 10.1038/nature19771. Epub 2016 Sep 28. Nature. 2016. PMID: 27680702 Free PMC article.
131 results