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180 results

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Page 1
In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: lebrasseur nk. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. Aging (Albany NY). 2023. PMID: 37154858 Free PMC article.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: lebrasseur nk. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
Biomarkers of cellular senescence in idiopathic pulmonary fibrosis.
Aversa Z, Atkinson EJ, Carmona EM, White TA, Heeren AA, Jachim SK, Zhang X, Cummings SR, Chiarella SE, Limper AH, LeBrasseur NK. Aversa Z, et al. Among authors: lebrasseur nk. Respir Res. 2023 Apr 7;24(1):101. doi: 10.1186/s12931-023-02403-8. Respir Res. 2023. PMID: 37029417 Free PMC article.
High prevalence of frailty in patients with adrenal adenomas and adrenocortical hormone excess: a cross-sectional multi-centre study with prospective enrolment.
Dogra P, Šambula L, Saini J, Thangamuthu K, Athimulam S, Delivanis DA, Baikousi DA, Nathani R, Zhang CD, Genere N, Salman Z, Turcu AF, Ambroziak U, Garcia RG, Achenbach SJ, Atkinson EJ, Singh S, LeBrasseur NK, Kastelan D, Bancos I. Dogra P, et al. Among authors: lebrasseur nk. Eur J Endocrinol. 2023 Sep 1;189(3):318-326. doi: 10.1093/ejendo/lvad113. Eur J Endocrinol. 2023. PMID: 37590964 Free PMC article.
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial.
Justice JN, Leng XI, LeBrasseur NK, Tchkonia T, Kirkland JL, Mitin N, Liu Y, Kritchevsky SB, Nicklas BJ, Ding J. Justice JN, et al. Among authors: lebrasseur nk. J Gerontol A Biol Sci Med Sci. 2024 Jan 1;79(1):glad214. doi: 10.1093/gerona/glad214. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37738560 Free PMC article. Clinical Trial.
BMAL1 modulates senescence programming via AP-1.
Jachim SK, Zhong J, Ordog T, Lee JH, Bhagwate AV, Nagaraj NK, Westendorf JJ, Passos JF, Matveyenko AV, LeBrasseur NK. Jachim SK, et al. Among authors: lebrasseur nk. Aging (Albany NY). 2023 Oct 10;15(19):9984-10009. doi: 10.18632/aging.205112. Epub 2023 Oct 10. Aging (Albany NY). 2023. PMID: 37819791 Free PMC article.
Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.
Englund DA, Jolliffe AM, Hanson GJ, Aversa Z, Zhang X, Jiang X, White TA, Zhang L, Monroe DG, Robbins PD, Niedernhofer LJ, Kamenecka TM, Khosla S, LeBrasseur NK. Englund DA, et al. Among authors: lebrasseur nk. JCI Insight. 2024 Jan 23;9(2):e169512. doi: 10.1172/jci.insight.169512. JCI Insight. 2024. PMID: 38051584 Free PMC article.
The Fourth Annual Symposium of the Midwest Aging Consortium.
Kim J, Buffenstein R, Bronikowski AM, Pilar Vanegas ND, Rosas L, Agudelo-Garcia P, Mora AL, Rojas M, Englund DA, LeBrasseur NK, Nunes A, Robbins PD, Kohut ML, Kothadiya S, Bardhan R, Camell CD, Sturmlechner I, Goronzy JJ, Yeh CY, Lamming DW, Huang S, Leiser SF, Escorcia W, Gill MS, Taylor JR, Helfand SL, Korm S, Gribble KE, Pehar M, Blaszkiewicz M, Townsend KL, McGregor ER, Anderson RM, Stilgenbauer L, Sadagurski M, Taylor A, McNeill E, Stoeger T, Bai H. Kim J, et al. Among authors: lebrasseur nk. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae236. doi: 10.1093/gerona/glae236. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39498863 Free PMC article.
Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability.
Nambiar A, Kellogg D 3rd, Justice J, Goros M, Gelfond J, Pascual R, Hashmi S, Masternak M, Prata L, LeBrasseur N, Limper A, Kritchevsky S, Musi N, Tchkonia T, Kirkland J. Nambiar A, et al. EBioMedicine. 2023 Apr;90:104481. doi: 10.1016/j.ebiom.2023.104481. Epub 2023 Feb 28. EBioMedicine. 2023. PMID: 36857968 Free PMC article. Clinical Trial.
180 results