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TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, Li R, Wernig M, Wong WH, Chang HY, Oro AE. Li L, et al. Among authors: gaddam s. Cell Stem Cell. 2019 Feb 7;24(2):271-284.e8. doi: 10.1016/j.stem.2018.12.012. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686763 Free PMC article.
c-FOS drives reversible basal to squamous cell carcinoma transition.
Kuonen F, Li NY, Haensel D, Patel T, Gaddam S, Yerly L, Rieger K, Aasi S, Oro AE. Kuonen F, et al. Among authors: gaddam s. Cell Rep. 2021 Oct 5;37(1):109774. doi: 10.1016/j.celrep.2021.109774. Cell Rep. 2021. PMID: 34610301 Free PMC article.
Gibbin mesodermal regulation patterns epithelial development.
Collier A, Liu A, Torkelson J, Pattison J, Gaddam S, Zhen H, Patel T, McCarthy K, Ghanim H, Oro AE. Collier A, et al. Among authors: gaddam s. Nature. 2022 Jun;606(7912):188-196. doi: 10.1038/s41586-022-04727-9. Epub 2022 May 18. Nature. 2022. PMID: 35585237 Free PMC article.
LY6D marks pre-existing resistant basosquamous tumor subpopulations.
Haensel D, Gaddam S, Li NY, Gonzalez F, Patel T, Cloutier JM, Sarin KY, Tang JY, Rieger KE, Aasi SZ, Oro AE. Haensel D, et al. Among authors: gaddam s. Nat Commun. 2022 Dec 6;13(1):7520. doi: 10.1038/s41467-022-35020-y. Nat Commun. 2022. PMID: 36473848 Free PMC article.
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Bruckner A, Bilousova G, Roop D, Bailey I, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: gaddam s. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.529447. doi: 10.1101/2023.02.28.529447. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 11;15(1):5834. doi: 10.1038/s41467-024-49400-z PMID: 36909618 Free PMC article. Updated. Preprint.
305 results