Beese LS - Search Results

1

Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics.

Wang Y, Shi Y, Hellinga HW, Beese LS. Wang Y, et al. Among authors: beese ls. Nucleic Acids Res. 2023 Jun 23;51(11):5883-5894. doi: 10.1093/nar/gkad368. Nucleic Acids Res. 2023. PMID: 37166959 Free PMC article.

2

Structure of DNA polymerase I Klenow fragment bound to duplex DNA.

Beese LS, Derbyshire V, Steitz TA. Beese LS, et al. Science. 1993 Apr 16;260(5106):352-5. doi: 10.1126/science.8469987. Science. 1993. PMID: 8469987

3

Contact x-ray microscopy. A new technique for imaging cellular fine structure.

Beese L, Feder R, Sayre D. Beese L, et al. Biophys J. 1986 Jan;49(1):259-68. doi: 10.1016/S0006-3495(86)83639-6. Biophys J. 1986. PMID: 3955174 Free PMC article.

4

Covalent protein-oligonucleotide conjugates by copper-free click reaction.

Khatwani SL, Kang JS, Mullen DG, Hast MA, Beese LS, Distefano MD, Taton TA. Khatwani SL, et al. Among authors: beese ls. Bioorg Med Chem. 2012 Jul 15;20(14):4532-9. doi: 10.1016/j.bmc.2012.05.017. Epub 2012 May 17. Bioorg Med Chem. 2012. PMID: 22682299 Free PMC article.

5

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase.

Eastman RT, White J, Hucke O, Yokoyama K, Verlinde CL, Hast MA, Beese LS, Gelb MH, Rathod PK, Van Voorhis WC. Eastman RT, et al. Among authors: beese ls. Mol Biochem Parasitol. 2007 Mar;152(1):66-71. doi: 10.1016/j.molbiopara.2006.11.012. Epub 2006 Dec 22. Mol Biochem Parasitol. 2007. PMID: 17208314 Free PMC article.

6

Rapid analysis of protein farnesyltransferase substrate specificity using peptide libraries and isoprenoid diphosphate analogues.

Wang YC, Dozier JK, Beese LS, Distefano MD. Wang YC, et al. Among authors: beese ls. ACS Chem Biol. 2014 Aug 15;9(8):1726-35. doi: 10.1021/cb5002312. Epub 2014 Jun 5. ACS Chem Biol. 2014. PMID: 24841702 Free PMC article.

7

Microtubule structure at 18 A resolution.

Beese L, Stubbs G, Cohen C. Beese L, et al. J Mol Biol. 1987 Mar 20;194(2):257-64. doi: 10.1016/0022-2836(87)90373-1. J Mol Biol. 1987. PMID: 3612805

8

The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.

Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS. Long SB, et al. Among authors: beese ls. Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):12948-53. doi: 10.1073/pnas.241407898. Epub 2001 Oct 30. Proc Natl Acad Sci U S A. 2001. PMID: 11687658 Free PMC article.

9

The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.

Cuneo MJ, Changela A, Warren JJ, Beese LS, Hellinga HW. Cuneo MJ, et al. Among authors: beese ls. J Mol Biol. 2006 Sep 15;362(2):259-70. doi: 10.1016/j.jmb.2006.06.084. Epub 2006 Aug 10. J Mol Biol. 2006. PMID: 16904687

10

Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein.

Tian Y, Cuneo MJ, Changela A, Höcker B, Beese LS, Hellinga HW. Tian Y, et al. Among authors: beese ls. Protein Sci. 2007 Oct;16(10):2240-50. doi: 10.1110/ps.072969407. Epub 2007 Aug 31. Protein Sci. 2007. PMID: 17766373 Free PMC article.

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