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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.
Darwich AS, Ogungbenro K, Vinks AA, Powell JR, Reny JL, Marsousi N, Daali Y, Fairman D, Cook J, Lesko LJ, McCune JS, Knibbe C, de Wildt SN, Leeder JS, Neely M, Zuppa AF, Vicini P, Aarons L, Johnson TN, Boiani J, Rostami-Hodjegan A. Darwich AS, et al. Among authors: de wildt sn. Clin Pharmacol Ther. 2017 May;101(5):646-656. doi: 10.1002/cpt.659. Epub 2017 Apr 4. Clin Pharmacol Ther. 2017. PMID: 28182269 Review.
Roles of Clinical Research Networks in Pediatric Drug Development.
Turner MA, Attar S, de Wildt SN, Vassal G, Mangiarini L, Giaquinto C. Turner MA, et al. Among authors: de wildt sn. Clin Ther. 2017 Oct;39(10):1939-1948. doi: 10.1016/j.clinthera.2017.09.001. Epub 2017 Sep 22. Clin Ther. 2017. PMID: 28943118 Review.
Dose-linearity of the pharmacokinetics of an intravenous [14 C]midazolam microdose in children.
van Groen BD, Vaes WH, Park BK, Krekels EHJ, van Duijn E, Kõrgvee LT, Maruszak W, Grynkiewicz G, Garner RC, Knibbe CAJ, Tibboel D, de Wildt SN, Turner MA. van Groen BD, et al. Among authors: de wildt sn. Br J Clin Pharmacol. 2019 Oct;85(10):2332-2340. doi: 10.1111/bcp.14047. Epub 2019 Jul 30. Br J Clin Pharmacol. 2019. PMID: 31269280 Free PMC article.
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology.
Schrier L, Hadjipanayis A, Stiris T, Ross-Russell RI, Valiulis A, Turner MA, Zhao W, De Cock P, de Wildt SN, Allegaert K, van den Anker J. Schrier L, et al. Among authors: de cock p, de wildt sn. Eur J Pediatr. 2020 May;179(5):839-847. doi: 10.1007/s00431-019-03556-9. Epub 2020 Jan 3. Eur J Pediatr. 2020. PMID: 31897842
Pediatric Pharmacokinetics and Dose Predictions: A Report of a Satellite Meeting to the 10th Juvenile Toxicity Symposium.
van Groen BD, Pilla Reddy V, Badée J, Olivares-Morales A, Johnson TN, Nicolaï J, Annaert P, Smits A, de Wildt SN, Knibbe CAJ, de Zwart L. van Groen BD, et al. Among authors: de wildt sn, de zwart l. Clin Transl Sci. 2021 Jan;14(1):29-35. doi: 10.1111/cts.12843. Epub 2020 Aug 3. Clin Transl Sci. 2021. PMID: 32702198 Free PMC article. Review.
The conect4children (c4c) Consortium: Potential for Improving European Clinical Research into Medicines for Children.
Turner MA, Hildebrand H, Fernandes RM, de Wildt SN, Mahler F, Hankard R, Leary R, Bonifazi F, Nobels P, Cheng K, Attar S, Rossi P, Rocchi F, Claverol J, Nafria B, Giaquinto C. Turner MA, et al. Among authors: de wildt sn. Pharmaceut Med. 2021 Mar;35(2):71-79. doi: 10.1007/s40290-020-00373-6. Epub 2021 Feb 4. Pharmaceut Med. 2021. PMID: 33539007 Free PMC article.
Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.
Smits A, Annaert P, Cavallaro G, De Cock PAJG, de Wildt SN, Kindblom JM, Lagler FB, Moreno C, Pokorna P, Schreuder MF, Standing JF, Turner MA, Vitiello B, Zhao W, Weingberg AM, Willmann R, van den Anker J, Allegaert K. Smits A, et al. Among authors: de cock pajg, de wildt sn. Br J Clin Pharmacol. 2022 Dec;88(12):4965-4984. doi: 10.1111/bcp.14958. Epub 2021 Jul 23. Br J Clin Pharmacol. 2022. PMID: 34180088 Free PMC article. Review.
253 results