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CDK12/13 dual inhibitors are potential therapeutics for acute myeloid leukemia.
Savoy L, Long N, Lee H, Chen R, Allen B, Lin HY, Tognon C, V Malhotra S, Tyner JW, Zhang H. Savoy L, et al. Among authors: tognon c. Br J Haematol. 2023 Jul;202(1):195-198. doi: 10.1111/bjh.18843. Epub 2023 May 14. Br J Haematol. 2023. PMID: 37182843 Free PMC article. No abstract available.
The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation.
Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo AR, Kool M, Agnihotri S, El-Naggar A, Yu B, Somasekharan SP, Faubert B, Bridon G, Tognon CE, Mathers J, Thomas R, Li A, Barokas A, Kwok B, Bowden M, Smith S, Wu X, Korshunov A, Hielscher T, Northcott PA, Galpin JD, Ahern CA, Wang Y, McCabe MG, Collins VP, Jones RG, Pollak M, Delattre O, Gleave ME, Jan E, Pfister SM, Proud CG, Derry WB, Taylor MD, Sorensen PH. Leprivier G, et al. Cell. 2013 May 23;153(5):1064-79. doi: 10.1016/j.cell.2013.04.055. Cell. 2013. PMID: 23706743 Free PMC article.
On translational regulation and EMT.
Evdokimova V, Tognon CE, Sorensen PH. Evdokimova V, et al. Semin Cancer Biol. 2012 Oct;22(5-6):437-45. doi: 10.1016/j.semcancer.2012.04.007. Epub 2012 Apr 23. Semin Cancer Biol. 2012. PMID: 22554796 Review.
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