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Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain.
Ogata A, Yamada T, Hattori S, Ikenuma H, Abe J, Tada M, Ichise M, Suzuki M, Ito K, Kato T, Amaike K, Hirota T, Kakita A, Itami K, Kimura Y. Ogata A, et al. Among authors: suzuki m. Bioorg Med Chem Lett. 2023 Jun 15;90:129327. doi: 10.1016/j.bmcl.2023.129327. Epub 2023 May 13. Bioorg Med Chem Lett. 2023. PMID: 37187253
Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma.
Koyama H, Ikenuma H, Toda H, Kondo G, Hirano M, Kato M, Abe J, Yamada T, Wakabayashi T, Ito K, Natsume A, Suzuki M. Koyama H, et al. Among authors: suzuki m. Bioorg Med Chem Lett. 2017 May 1;27(9):1892-1896. doi: 10.1016/j.bmcl.2017.03.045. Epub 2017 Mar 18. Bioorg Med Chem Lett. 2017. PMID: 28363750
Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11C]acetone.
Ikenuma H, Koyama H, Kajino N, Kimura Y, Ogata A, Abe J, Kawasumi Y, Kato T, Takashima A, Ito K, Suzuki M. Ikenuma H, et al. Among authors: suzuki m. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2107-2111. doi: 10.1016/j.bmcl.2019.07.005. Epub 2019 Jul 3. Bioorg Med Chem Lett. 2019. PMID: 31311732
11C-Labeling of acyclic retinoid peretinoin by rapid C-[11C]methylation to disclose novel brain permeability and central nervous system activities hidden in antitumor agent.
Suzuki K, Koyama H, Nakamura N, Kimura Y, Ogata A, Ikenuma H, Ishii H, Zhang MR, Kawamura K, Minamimoto T, Nagai Y, Katsuki H, Kimura T, Kimura N, Ichise M, Kato T, Ito K, Suzuki M. Suzuki K, et al. Among authors: suzuki m. Bioorg Med Chem Lett. 2023 Apr 1;85:129212. doi: 10.1016/j.bmcl.2023.129212. Epub 2023 Mar 3. Bioorg Med Chem Lett. 2023. PMID: 36871703
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