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Huntingtin Decreases Susceptibility to a Spontaneous Seizure Disorder in FVN/B Mice.
Van Raamsdonk JM, Al-Shekaili HH, Wagner L, Bredy TW, Chan L, Pearson J, Schwab C, Murphy Z, Devon RS, Lu G, Kobor MS, Hayden MR, Leavitt BR. Van Raamsdonk JM, et al. Among authors: hayden mr. Aging Dis. 2023 Dec 1;14(6):2249-2266. doi: 10.14336/AD.2023.0423. Aging Dis. 2023. PMID: 37199581 Free PMC article.
Cerebrospinal fluid biomarkers for assessing Huntington disease onset and severity.
Caron NS, Haqqani AS, Sandhu A, Aly AE, Findlay Black H, Bone JN, McBride JL, Abulrob A, Stanimirovic D, Leavitt BR, Hayden MR. Caron NS, et al. Among authors: hayden mr. Brain Commun. 2022 Nov 25;4(6):fcac309. doi: 10.1093/braincomms/fcac309. eCollection 2022. Brain Commun. 2022. PMID: 36523269 Free PMC article.
Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease.
Caron NS, Aly AE, Findlay Black H, Martin DDO, Schmidt ME, Ko S, Anderson C, Harvey EM, Casal LL, Anderson LM, Rahavi SMR, Reid GSD, Oda MN, Stanimirovic D, Abulrob A, McBride JL, Leavitt BR, Hayden MR. Caron NS, et al. Among authors: hayden mr. J Control Release. 2024 Mar;367:27-44. doi: 10.1016/j.jconrel.2024.01.011. Epub 2024 Jan 24. J Control Release. 2024. PMID: 38215984 Free article.
Towards Standardizing Nomenclature in Huntington's Disease Research.
DiFiglia M, Leavitt BR, Macdonald D, Thompson LM; Huntington’s Disease Nomenclature Working Group:. DiFiglia M, et al. J Huntingtons Dis. 2024;13(2):119-131. doi: 10.3233/JHD-240044. J Huntingtons Dis. 2024. PMID: 38968054 Free PMC article. Review.
Safety and efficacy of laquinimod for Huntington's disease (LEGATO-HD): a multicentre, randomised, double-blind, placebo-controlled, phase 2 study.
Reilmann R, Anderson KE, Feigin A, Tabrizi SJ, Leavitt BR, Stout JC, Piccini P, Schubert R, Loupe P, Wickenberg A, Borowsky B, Rynkowski G, Volkinshtein R, Li T, Savola JM, Hayden M, Gordon MF; LEGATO-HD Study Group. Reilmann R, et al. Lancet Neurol. 2024 Mar;23(3):243-255. doi: 10.1016/S1474-4422(23)00454-4. Epub 2024 Jan 24. Lancet Neurol. 2024. PMID: 38280392 Clinical Trial.
Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models.
Joachimiak P, Ciesiołka A, Kozłowska E, Świtoński PM, Figura G, Ciołak A, Adamek G, Surdyka M, Kalinowska-Pośka Ż, Figiel M, Caron NS, Hayden MR, Fiszer A. Joachimiak P, et al. Among authors: hayden mr. BMC Biol. 2023 Feb 1;21(1):17. doi: 10.1186/s12915-023-01515-3. BMC Biol. 2023. PMID: 36726088 Free PMC article.
Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks.
Aly AE, Caron NS, Black HF, Schmidt ME, Anderson C, Ko S, Baddeley HJE, Anderson L, Casal LL, Rahavi RSM, Martin DDO, Hayden MR. Aly AE, et al. Among authors: hayden mr. J Control Release. 2023 Aug;360:913-927. doi: 10.1016/j.jconrel.2023.07.027. Epub 2023 Jul 27. J Control Release. 2023. PMID: 37468110 Free article.
900 results