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Integrative transcriptomic and metabolic analyses of the mammalian hibernating brain identifies a key role for succinate dehydrogenase in ischemic tolerance.
Bernstock JD, Willis CM, Garcia-Segura ME, Gaude E, Anni D, Lee YJ, Thomas LW, Casey A, Vicario N, Leonardi T, Nicaise AM, Gessler FA, Izzy S, Buffelli MR, Seidlitz J, Srinivasan S, Murphy MP, Ashcroft M, Cambiaghi M, Hallenbeck JM, Peruzzotti-Jametti L. Bernstock JD, et al. Among authors: nicaise am. bioRxiv [Preprint]. 2023 Mar 30:2023.03.29.534718. doi: 10.1101/2023.03.29.534718. bioRxiv. 2023. PMID: 37205496 Free PMC article. Preprint.
The neural stem cell secretome and its role in brain repair.
Willis CM, Nicaise AM, Peruzzotti-Jametti L, Pluchino S. Willis CM, et al. Among authors: nicaise am. Brain Res. 2020 Feb 15;1729:146615. doi: 10.1016/j.brainres.2019.146615. Epub 2019 Dec 19. Brain Res. 2020. PMID: 31863730 Free article. Review.
Stem Cells of the Aging Brain.
Nicaise AM, Willis CM, Crocker SJ, Pluchino S. Nicaise AM, et al. Front Aging Neurosci. 2020 Aug 6;12:247. doi: 10.3389/fnagi.2020.00247. eCollection 2020. Front Aging Neurosci. 2020. PMID: 32848716 Free PMC article. Review.
Harnessing the Neural Stem Cell Secretome for Regenerative Neuroimmunology.
Willis CM, Nicaise AM, Hamel R, Pappa V, Peruzzotti-Jametti L, Pluchino S. Willis CM, et al. Among authors: nicaise am. Front Cell Neurosci. 2020 Nov 5;14:590960. doi: 10.3389/fncel.2020.590960. eCollection 2020. Front Cell Neurosci. 2020. PMID: 33250716 Free PMC article. Review.
Astrocytic TIMP-1 regulates production of Anastellin, a novel inhibitor of oligodendrocyte differentiation and FTY720 responses.
Sutter PA, Willis CM, Menoret A, Nicaise AM, Sacino A, Sikkema AH, Jellison E, Win KK, Han DK, Church W, Baron W, Vella AT, Crocker SJ. Sutter PA, et al. Among authors: nicaise am. bioRxiv [Preprint]. 2023 Feb 18:2023.02.17.529003. doi: 10.1101/2023.02.17.529003. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2306816121. doi: 10.1073/pnas.2306816121 PMID: 36824834 Free PMC article. Updated. Preprint.
Mitochondrial reverse electron transport in myeloid cells perpetuates neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Hamel R, Krzak G, Reisz JA, Prag HA, Wu V, Xiang Y, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Vincent AE, Frezza C, Viscomi C, Marioni JC, D'Alessandro A, Takats Z, Murphy MP, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: nicaise am. bioRxiv [Preprint]. 2024 Jan 4:2024.01.03.574059. doi: 10.1101/2024.01.03.574059. bioRxiv. 2024. PMID: 38260262 Free PMC article. Preprint.
Mitochondrial complex I activity in microglia sustains neuroinflammation.
Peruzzotti-Jametti L, Willis CM, Krzak G, Hamel R, Pirvan L, Ionescu RB, Reisz JA, Prag HA, Garcia-Segura ME, Wu V, Xiang Y, Barlas B, Casey AM, van den Bosch AMR, Nicaise AM, Roth L, Bates GR, Huang H, Prasad P, Vincent AE, Frezza C, Viscomi C, Balmus G, Takats Z, Marioni JC, D'Alessandro A, Murphy MP, Mohorianu I, Pluchino S. Peruzzotti-Jametti L, et al. Among authors: nicaise am. Nature. 2024 Apr;628(8006):195-203. doi: 10.1038/s41586-024-07167-9. Epub 2024 Mar 13. Nature. 2024. PMID: 38480879 Free PMC article.
Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis.
Ionescu RB, Nicaise AM, Reisz JA, Williams EC, Prasad P, Willis CM, Simões-Abade MBC, Sbarro L, Dzieciatkowska M, Stephenson D, Suarez Cubero M, Rizzi S, Pirvan L, Peruzzotti-Jametti L, Fossati V, Edenhofer F, Leonardi T, Frezza C, Mohorianu I, D'Alessandro A, Pluchino S. Ionescu RB, et al. Among authors: nicaise am. Cell Stem Cell. 2024 Nov 7;31(11):1574-1590.e11. doi: 10.1016/j.stem.2024.09.014. Epub 2024 Oct 21. Cell Stem Cell. 2024. PMID: 39437792 Free article.
36 results