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Environmental sphagnum-associated fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.
Malhotra N, Oh S, Finin P, Medrano J, Andrews J, Goodwin M, Markowitz TE, Lack J, Boshoff HIM, Barry CE. Malhotra N, et al. Among authors: finin p. bioRxiv [Preprint]. 2024 Sep 23:2024.09.23.614403. doi: 10.1101/2024.09.23.614403. bioRxiv. 2024. Update in: PLoS Biol. 2024 Dec 3;22(12):e3002852. doi: 10.1371/journal.pbio.3002852 PMID: 39372785 Free PMC article. Updated. Preprint.
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.
Murugesan D, Ray PC, Bayliss T, Prosser GA, Harrison JR, Green K, Soares de Melo C, Feng TS, Street LJ, Chibale K, Warner DF, Mizrahi V, Epemolu O, Scullion P, Ellis L, Riley J, Shishikura Y, Ferguson L, Osuna-Cabello M, Read KD, Green SR, Lamprecht DA, Finin PM, Steyn AJC, Ioerger TR, Sacchettini J, Rhee KY, Arora K, Barry CE 3rd, Wyatt PG, Boshoff HIM. Murugesan D, et al. Among authors: finin pm. ACS Infect Dis. 2018 Jun 8;4(6):954-969. doi: 10.1021/acsinfecdis.7b00275. Epub 2018 Mar 26. ACS Infect Dis. 2018. PMID: 29522317 Free PMC article.