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A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. de Jong TV, et al. Among authors: chen d, chen h. bioRxiv [Preprint]. 2023 Sep 28:2023.04.13.536694. doi: 10.1101/2023.04.13.536694. bioRxiv. 2023. Update in: Cell Genom. 2024 Apr 10;4(4):100527. doi: 10.1016/j.xgen.2024.100527 PMID: 37214860 Free PMC article. Updated. Preprint.
The Wistar Kyoto Rat: A Model of Depression Traits.
Redei EE, Udell ME, Solberg Woods LC, Chen H. Redei EE, et al. Among authors: chen h. Curr Neuropharmacol. 2023;21(9):1884-1905. doi: 10.2174/1570159X21666221129120902. Curr Neuropharmacol. 2023. PMID: 36453495 Free PMC article.
An exponential increase in QTL detection with an increased sample size.
Chitre AS, Polesskaya O, Munro D, Cheng R, Mohammadi P, Holl K, Gao J, Bimschleger H, Martinez AG, George AM, Gileta AF, Han W, Horvath A, Hughson A, Ishiwari K, King CP, Lamparelli A, Versaggi CL, Martin CD, St Pierre CL, Tripi JA, Richards JB, Wang T, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Palmer AA. Chitre AS, et al. Among authors: chen h. Genetics. 2023 May 26;224(2):iyad054. doi: 10.1093/genetics/iyad054. Genetics. 2023. PMID: 36974931 Free PMC article.
Automated quantitative trait locus analysis (AutoQTL).
Freda PJ, Ghosh A, Zhang E, Luo T, Chitre AS, Polesskaya O, St Pierre CL, Gao J, Martin CD, Chen H, Garcia-Martinez AG, Wang T, Han W, Ishiwari K, Meyer P, Lamparelli A, King CP, Palmer AA, Li R, Moore JH. Freda PJ, et al. Among authors: chen h. BioData Min. 2023 Apr 10;16(1):14. doi: 10.1186/s13040-023-00331-3. BioData Min. 2023. PMID: 37038201 Free PMC article.
Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks.
Wright SN, Leger BS, Rosenthal SB, Liu SN, Jia T, Chitre AS, Polesskaya O, Holl K, Gao J, Cheng R, Garcia Martinez A, George A, Gileta AF, Han W, Netzley AH, King CP, Lamparelli A, Martin C, St Pierre CL, Wang T, Bimschleger H, Richards J, Ishiwari K, Chen H, Flagel SB, Meyer P, Robinson TE, Solberg Woods LC, Kreisberg JF, Ideker T, Palmer AA. Wright SN, et al. Among authors: chen h. Cell Rep. 2023 Aug 29;42(8):112873. doi: 10.1016/j.celrep.2023.112873. Epub 2023 Jul 31. Cell Rep. 2023. PMID: 37527041 Free PMC article.
A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. de Jong TV, et al. Among authors: chen d, chen h. Cell Genom. 2024 Apr 10;4(4):100527. doi: 10.1016/j.xgen.2024.100527. Epub 2024 Mar 26. Cell Genom. 2024. PMID: 38537634 Free PMC article.
Genomic Loci Influencing Cue-Reactivity in Heterogeneous Stock Rats.
King CP, Chitre AS, Leal-Gutiérrez JD, Tripi JA, Hughson AR, Horvath AP, Lamparelli AC, George A, Martin C, Pierre CLS, Sanches T, Bimschleger HV, Gao J, Cheng R, Nguyen KM, Holl KL, Polesskaya O, Ishiwari K, Chen H, Woods LCS, Palmer AA, Robinson TE, Flagel SB, Meyer PJ. King CP, et al. Among authors: chen h. bioRxiv [Preprint]. 2024 Apr 3:2024.03.13.584852. doi: 10.1101/2024.03.13.584852. bioRxiv. 2024. PMID: 38559127 Free PMC article. Preprint.
Y and mitochondrial chromosomes in the heterogeneous stock rat population.
Okamoto F, Chitre AS, Missfeldt Sanches T, Chen D, Munro D, Aron AT, Beeson A, Bimschleger HV, Eid M, Garcia Martinez AG, Han W, Holl K, Jackson T, Johnson BB, King CP, Kuhn BN, Lamparelli AC, Netzley AH, Nguyen KH, Peng BF, Tripi JA, Wang T, Ziegler KS, Adams DJ, Baud A, Carrette LLG, Chen H, de Guglielmo G, Dorrestein P, George O, Ishiwari K, Jablonski MM, Jhou TC, Kallupi M, Knight R, Meyer PJ, Solberg Woods LC, Polesskaya O, Palmer AA. Okamoto F, et al. Among authors: chen d, chen h. G3 (Bethesda). 2024 Nov 6;14(11):jkae213. doi: 10.1093/g3journal/jkae213. G3 (Bethesda). 2024. PMID: 39250761 Free PMC article.
Reversal of Biological Age in Multiple Rat Organs by Young Porcine Plasma Fraction.
Horvath S, Singh K, Raj K, Khairnar S, Sanghavi A, Shrivastava A, Zoller JA, Li CZ, Herenu CB, Canatelli-Mallat M, Lehmann M, Habazin S, Novokmet M, Vučković F, Woods LCS, Martinez AG, Wang T, Chiavellini P, Levine AJ, Chen H, Brooke RT, Gordevicius J, Lauc G, Goya RG, Katcher HL. Horvath S, et al. Among authors: chen h. bioRxiv [Preprint]. 2023 Aug 7:2023.08.06.552148. doi: 10.1101/2023.08.06.552148. bioRxiv. 2023. Update in: Geroscience. 2024 Feb;46(1):367-394. doi: 10.1007/s11357-023-00980-6 PMID: 37609328 Free PMC article. Updated. Preprint.
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