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β-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion.
Oger F, Bourouh C, Friano ME, Courty E, Rolland L, Gromada X, Moreno M, Carney C, Rabhi N, Durand E, Amanzougarene S, Berberian L, Derhourhi M, Blanc E, Hannou SA, Denechaud PD, Benfodda Z, Meffre P, Fajas L, Kerr-Conte J, Pattou F, Froguel P, Pourcet B, Bonnefond A, Collombat P, Annicotte JS. Oger F, et al. Among authors: denechaud pd. Diabetes. 2023 Aug 1;72(8):1112-1126. doi: 10.2337/db22-0604. Diabetes. 2023. PMID: 37216637
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, Auwerx J, Fajas L, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: denechaud pd. Cell Rep. 2016 May 3;15(5):1051-1061. doi: 10.1016/j.celrep.2016.03.079. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117420 Free article.
E2F1, a Novel Regulator of Metabolism.
Denechaud PD, Fajas L, Giralt A. Denechaud PD, et al. Front Endocrinol (Lausanne). 2017 Nov 10;8:311. doi: 10.3389/fendo.2017.00311. eCollection 2017. Front Endocrinol (Lausanne). 2017. PMID: 29176962 Free PMC article. Review.
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
Denechaud PD, Lopez-Mejia IC, Giralt A, Lai Q, Blanchet E, Delacuisine B, Nicolay BN, Dyson NJ, Bonner C, Pattou F, Annicotte JS, Fajas L. Denechaud PD, et al. J Clin Invest. 2016 Jan;126(1):137-50. doi: 10.1172/JCI81542. Epub 2015 Nov 30. J Clin Invest. 2016. PMID: 26619117 Free PMC article.
Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR.
Castellano-Castillo D, Denechaud PD, Fajas L, Moreno-Indias I, Oliva-Olivera W, Tinahones F, Queipo-Ortuño MI, Cardona F. Castellano-Castillo D, et al. Among authors: denechaud pd. PLoS One. 2019 Apr 8;14(4):e0215083. doi: 10.1371/journal.pone.0215083. eCollection 2019. PLoS One. 2019. PMID: 30958852 Free PMC article.
34 results