Cochrane SA - Search Results

1

Targeting membrane-bound bacterial cell wall precursors: a tried and true antibiotic strategy in nature and the clinic.

Buijs NP, Matheson EJ, Cochrane SA, Martin NI. Buijs NP, et al. Among authors: cochrane sa. Chem Commun (Camb). 2023 Jun 20;59(50):7685-7703. doi: 10.1039/d3cc01070h. Chem Commun (Camb). 2023. PMID: 37219335 Review.

2

Molecular cloning and characterization of drimenol synthase from valerian plant (Valeriana officinalis).

Kwon M, Cochrane SA, Vederas JC, Ro DK. Kwon M, et al. Among authors: cochrane sa. FEBS Lett. 2014 Dec 20;588(24):4597-603. doi: 10.1016/j.febslet.2014.10.031. Epub 2014 Nov 4. FEBS Lett. 2014. PMID: 25447532 Free article.

3

Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria.

Cochrane SA, Li X, He S, Yu M, Wu M, Vederas JC. Cochrane SA, et al. J Med Chem. 2015 Dec 24;58(24):9779-85. doi: 10.1021/acs.jmedchem.5b01578. Epub 2015 Dec 4. J Med Chem. 2015. PMID: 26636619

4

Unacylated tridecaptin A₁ acts as an effective sensitiser of Gram-negative bacteria to other antibiotics.

Cochrane SA, Vederas JC. Cochrane SA, et al. Int J Antimicrob Agents. 2014 Dec;44(6):493-9. doi: 10.1016/j.ijantimicag.2014.08.008. Epub 2014 Sep 27. Int J Antimicrob Agents. 2014. PMID: 25315408

5

Solid supported chemical syntheses of both components of the lantibiotic lacticin 3147.

Liu W, Chan AS, Liu H, Cochrane SA, Vederas JC. Liu W, et al. Among authors: cochrane sa. J Am Chem Soc. 2011 Sep 14;133(36):14216-9. doi: 10.1021/ja206017p. Epub 2011 Aug 17. J Am Chem Soc. 2011. PMID: 21848315

6

Synthesis and structure-activity relationship studies of N-terminal analogues of the antimicrobial peptide tridecaptin A(1).

Cochrane SA, Lohans CT, Brandelli JR, Mulvey G, Armstrong GD, Vederas JC. Cochrane SA, et al. J Med Chem. 2014 Feb 13;57(3):1127-31. doi: 10.1021/jm401779d. Epub 2014 Jan 30. J Med Chem. 2014. PMID: 24479847

7

Total Synthesis and Stereochemical Assignment of the Antimicrobial Lipopeptide Cerexin A1.

Cochrane SA, Surgenor RR, Khey KM, Vederas JC. Cochrane SA, et al. Org Lett. 2015 Nov 6;17(21):5428-31. doi: 10.1021/acs.orglett.5b02779. Epub 2015 Oct 14. Org Lett. 2015. PMID: 26465807

8

Key residues in octyl-tridecaptin A1 analogues linked to stable secondary structures in the membrane.

Cochrane SA, Findlay B, Vederas JC, Ratemi ES. Cochrane SA, et al. Chembiochem. 2014 Jun 16;15(9):1295-9. doi: 10.1002/cbic.201402024. Epub 2014 May 9. Chembiochem. 2014. PMID: 24816483

9

Biochemical, structural, and genetic characterization of tridecaptin A₁, an antagonist of Campylobacter jejuni.

Lohans CT, van Belkum MJ, Cochrane SA, Huang Z, Sit CS, McMullen LM, Vederas JC. Lohans CT, et al. Among authors: cochrane sa. Chembiochem. 2014 Jan 24;15(2):243-9. doi: 10.1002/cbic.201300595. Epub 2013 Dec 30. Chembiochem. 2014. PMID: 24382692

10

Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II.

Cochrane SA, Findlay B, Bakhtiary A, Acedo JZ, Rodriguez-Lopez EM, Mercier P, Vederas JC. Cochrane SA, et al. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11561-11566. doi: 10.1073/pnas.1608623113. Epub 2016 Sep 29. Proc Natl Acad Sci U S A. 2016. PMID: 27688760 Free PMC article.

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