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Cell-based high-content approach for SARS-CoV-2 neutralization identifies unique monoclonal antibodies and PI3K pathway inhibitors.
Cabel CR, Guzman BA, Alizadeh E, Li S, Holberg C, Wichaidit C, Cusanovich DA, Paek AL, Thatcher GRJ, Doorslaer KV, Nargi RS, Sutton RE, Suryadevara N, Crowe JE, Carnahan RH, Campos SK, Thorne CA. Cabel CR, et al. Among authors: thorne ca. bioRxiv [Preprint]. 2024 Oct 7:2024.10.04.616743. doi: 10.1101/2024.10.04.616743. bioRxiv. 2024. PMID: 39416139 Free PMC article. Preprint.
SGRN: A Cas12a-driven Synthetic Gene Regulatory Network System.
Kang H, Fitch JC, Varghese RP, Thorne CA, Cusanovich DA. Kang H, et al. Among authors: thorne ca. bioRxiv [Preprint]. 2023 May 8:2023.05.08.539911. doi: 10.1101/2023.05.08.539911. bioRxiv. 2023. PMID: 37214915 Free PMC article. Preprint.
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Among authors: thorne ca. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
Feedback in the β-catenin destruction complex imparts bistability and cellular memory.
Cantoria MJ, Alizadeh E, Ravi J, Varghese RP, Bunnag N, Pond KW, Kettenbach AN, Ahmed Y, Paek AL, Tyson JJ, Doubrovinski K, Lee E, Thorne CA. Cantoria MJ, et al. Among authors: thorne ca. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2208787120. doi: 10.1073/pnas.2208787120. Epub 2023 Jan 4. Proc Natl Acad Sci U S A. 2023. PMID: 36598937 Free PMC article.
40 results