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Development of a population pharmacokinetic model to characterize the pharmacokinetics of intrathecally administered tominersen in cerebrospinal fluid and plasma.
Yamamoto Y, Sanwald Ducray P, Björnsson M, Smart K, Grimsey P, Vatakuti S, Portron A, Massonnet B, Norris DA, Silber Baumann HE. Yamamoto Y, et al. Among authors: norris da. CPT Pharmacometrics Syst Pharmacol. 2023 Sep;12(9):1213-1226. doi: 10.1002/psp4.13001. Epub 2023 Jun 13. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37221972 Free PMC article.
A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.
Biliouris K, Gaitonde P, Yin W, Norris DA, Wang Y, Henry S, Fey R, Nestorov I, Schmidt S, Rogge M, Lesko LJ, Trame MN. Biliouris K, et al. Among authors: norris da. CPT Pharmacometrics Syst Pharmacol. 2018 Sep;7(9):581-592. doi: 10.1002/psp4.12323. Epub 2018 Aug 16. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30043511 Free PMC article.
Targeting Huntingtin Expression in Patients with Huntington's Disease.
Tabrizi SJ, Leavitt BR, Landwehrmeyer GB, Wild EJ, Saft C, Barker RA, Blair NF, Craufurd D, Priller J, Rickards H, Rosser A, Kordasiewicz HB, Czech C, Swayze EE, Norris DA, Baumann T, Gerlach I, Schobel SA, Paz E, Smith AV, Bennett CF, Lane RM; Phase 1–2a IONIS-HTTRx Study Site Teams. Tabrizi SJ, et al. Among authors: norris da. N Engl J Med. 2019 Jun 13;380(24):2307-2316. doi: 10.1056/NEJMoa1900907. Epub 2019 May 6. N Engl J Med. 2019. PMID: 31059641 Clinical Trial.
232 results