Yaglom J - Search Results

1

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks.

Kumar S, Gahramanov V, Patel S, Yaglom J, Kaczmarczyk L, Alexandrov IA, Gerlitz G, Salmon-Divon M, Sherman MY. Kumar S, et al. Among authors: yaglom j. Int J Mol Sci. 2023 May 13;24(10):8717. doi: 10.3390/ijms24108717. Int J Mol Sci. 2023. PMID: 37240063 Free PMC article.

2

A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects.

Hesin A, Kumar S, Gahramanov V, Becker M, Vilenchik M, Alexandrov I, Yaglom J, Sherman MY. Hesin A, et al. Among authors: yaglom j. Cancers (Basel). 2022 Mar 8;14(6):1381. doi: 10.3390/cancers14061381. Cancers (Basel). 2022. PMID: 35326533 Free PMC article.

3

Oncogenes induce senescence with incomplete growth arrest and suppress the DNA damage response in immortalized cells.

Sherman MY, Meng L, Stampfer M, Gabai VL, Yaglom JA. Sherman MY, et al. Aging Cell. 2011 Dec;10(6):949-61. doi: 10.1111/j.1474-9726.2011.00736.x. Epub 2011 Sep 16. Aging Cell. 2011. PMID: 21824272 Free PMC article.

4

Oncogene-triggered suppression of DNA repair leads to DNA instability in cancer.

Yaglom JA, McFarland C, Mirny L, Sherman MY. Yaglom JA, et al. Oncotarget. 2014 Sep 30;5(18):8367-78. doi: 10.18632/oncotarget.2259. Oncotarget. 2014. PMID: 25252808 Free PMC article.

5

Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module.

Patel S, Kumar S, Baldan S, Hesin A, Yaglom J, Sherman MY. Patel S, et al. Among authors: yaglom j. iScience. 2022 Apr 22;25(5):104282. doi: 10.1016/j.isci.2022.104282. eCollection 2022 May 20. iScience. 2022. PMID: 35573186 Free PMC article.

6

Search for Synergistic Drug Combinations to Treat Chronic Lymphocytic Leukemia.

Hezkiy EE, Kumar S, Gahramanov V, Yaglom J, Hesin A, Jadhav SS, Guzev E, Patel S, Avinery E, Firer MA, Sherman MY. Hezkiy EE, et al. Among authors: yaglom j. Cells. 2022 Nov 18;11(22):3671. doi: 10.3390/cells11223671. Cells. 2022. PMID: 36429097 Free PMC article.

7

Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.

Gabai VL, Yaglom JA, Waldman T, Sherman MY. Gabai VL, et al. Mol Cell Biol. 2009 Jan;29(2):559-69. doi: 10.1128/MCB.01041-08. Epub 2008 Nov 10. Mol Cell Biol. 2009. PMID: 19001088 Free PMC article.

8

Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.

Yaglom JA, Wang Y, Li A, Li Z, Monti S, Alexandrov I, Lu X, Sherman MY. Yaglom JA, et al. Sci Rep. 2018 Feb 14;8(1):3010. doi: 10.1038/s41598-017-14900-0. Sci Rep. 2018. PMID: 29445088 Free PMC article.

9

High levels of heat shock protein Hsp72 in cancer cells suppress default senescence pathways.

Yaglom JA, Gabai VL, Sherman MY. Yaglom JA, et al. Cancer Res. 2007 Mar 1;67(5):2373-81. doi: 10.1158/0008-5472.CAN-06-3796. Cancer Res. 2007. PMID: 17332370

10

The Hsp70-Bag3 complex modulates the phosphorylation and nuclear translocation of Hippo pathway protein Yap.

Baldan S, Meriin AB, Yaglom J, Alexandrov I, Varelas X, Xiao ZJ, Sherman MY. Baldan S, et al. Among authors: yaglom j. J Cell Sci. 2021 Dec 1;134(23):jcs259107. doi: 10.1242/jcs.259107. Epub 2021 Dec 2. J Cell Sci. 2021. PMID: 34761265 Free PMC article.

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