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Massively parallel knock-in engineering of human T cells.
Dai X, Park JJ, Du Y, Na Z, Lam SZ, Chow RD, Renauer PA, Gu J, Xin S, Chu Z, Liao C, Clark P, Zhao H, Slavoff S, Chen S. Dai X, et al. Among authors: renauer pa. Nat Biotechnol. 2023 Sep;41(9):1239-1255. doi: 10.1038/s41587-022-01639-x. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702900 Free PMC article.
Applications of CRISPR technology in cellular immunotherapy.
Zhou X, Renauer PA, Zhou L, Fang SY, Chen S. Zhou X, et al. Among authors: renauer pa. Immunol Rev. 2023 Nov;320(1):199-216. doi: 10.1111/imr.13241. Epub 2023 Jul 14. Immunol Rev. 2023. PMID: 37449673 Free PMC article. Review.
CTLA-4 tail fusion enhances CAR-T antitumor immunity.
Zhou X, Cao H, Fang SY, Chow RD, Tang K, Majety M, Bai M, Dong MB, Renauer PA, Shang X, Suzuki K, Levchenko A, Chen S. Zhou X, et al. Among authors: renauer pa. Nat Immunol. 2023 Sep;24(9):1499-1510. doi: 10.1038/s41590-023-01571-5. Epub 2023 Jul 27. Nat Immunol. 2023. PMID: 37500885 Free PMC article.
Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT.
Baysoy A, Tian X, Zhang F, Renauer P, Bai Z, Shi H, Li H, Tao B, Yang M, Enninful A, Gao F, Wang G, Zhang W, Tran T, Patterson NH, Bao S, Dong C, Xin S, Zhong M, Rankin S, Guy C, Wang Y, Connelly JP, Pruett-Miller SM, Chi H, Chen S, Fan R. Baysoy A, et al. Among authors: renauer p. bioRxiv [Preprint]. 2024 Nov 19:2024.11.18.624106. doi: 10.1101/2024.11.18.624106. bioRxiv. 2024. PMID: 39605490 Free PMC article. Preprint.
Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function.
Renauer P, Park JJ, Bai M, Acosta A, Lee WH, Lin GH, Zhang Y, Dai X, Wang G, Errami Y, Wu T, Clark P, Ye L, Yang Q, Chen S. Renauer P, et al. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532663. doi: 10.1101/2023.03.14.532663. bioRxiv. 2023. Update in: Cancer Immunol Res. 2023 Aug 3;11(8):1068-1084. doi: 10.1158/2326-6066.CIR-22-0565 PMID: 36993638 Free PMC article. Updated. Preprint.
36 results