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Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma.
Kader T, Lin JR, Hug CB, Coy S, Chen YA, de Bruijn I, Shih N, Jung E, Pelletier RJ, Lopez Leon M, Mingo G, Omran DK, Lee JS, Yapp C, Satravada BA, Kundra R, Xu Y, Chan S, Tefft JB, Muhlich JL, Kim SH, Gysler SM, Agudo J, Heath JR, Schultz N, Drescher CW, Sorger PK, Drapkin R, Santagata S. Kader T, et al. Among authors: lin jr. Cancer Discov. 2024 Dec 20. doi: 10.1158/2159-8290.CD-24-1366. Online ahead of print. Cancer Discov. 2024. PMID: 39704522
Skin immune-mesenchymal interplay within tertiary lymphoid structures promotes autoimmune pathogenesis in hidradenitis suppurativa.
Yu WW, Barrett JNP, Tong J, Lin MJ, Marohn M, Devlin JC, Herrera A, Remark J, Levine J, Liu PK, Fang V, Zellmer AM, Oldridge DA, Wherry EJ, Lin JR, Chen JY, Sorger P, Santagata S, Krueger JG, Ruggles KV, Wang F, Su C, Koralov SB, Wang J, Chiu ES, Lu CP. Yu WW, et al. Among authors: lin jr. Immunity. 2024 Dec 10;57(12):2827-2842.e5. doi: 10.1016/j.immuni.2024.11.010. Immunity. 2024. PMID: 39662091
Ovarian cancer-derived IL-4 promotes immunotherapy resistance.
Mollaoglu G, Tepper A, Falcomatà C, Potak HT, Pia L, Amabile A, Mateus-Tique J, Rabinovich N, Park MD, LaMarche NM, Brody R, Browning L, Lin JR, Zamarin D, Sorger PK, Santagata S, Merad M, Baccarini A, Brown BD. Mollaoglu G, et al. Among authors: lin jr. Cell. 2024 Dec 26;187(26):7492-7510.e22. doi: 10.1016/j.cell.2024.10.006. Epub 2024 Oct 30. Cell. 2024. PMID: 39481380
Quality control for single-cell analysis of high-plex tissue profiles using CyLinter.
Baker GJ, Novikov E, Zhao Z, Vallius T, Davis JA, Lin JR, Muhlich JL, Mittendorf EA, Santagata S, Guerriero JL, Sorger PK. Baker GJ, et al. Among authors: lin jr. Nat Methods. 2024 Dec;21(12):2248-2259. doi: 10.1038/s41592-024-02328-0. Epub 2024 Oct 30. Nat Methods. 2024. PMID: 39478175 Free PMC article.
372 results