Naldini L - Search Results

1

Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders.

Colantuoni M, Jofra Hernandez R, Pettinato E, Basso-Ricci L, Magnani L, Andolfi G, Rigamonti C, Finardi A, Romeo V, Soldi M, Sergi Sergi L, Rocchi M, Scala S, Hoffman HM, Gregori S, Kajaste-Rudnitski A, Sanvito F, Muzio L, Naldini L, Aiuti A, Mortellaro A. Colantuoni M, et al. Among authors: naldini l. Sci Transl Med. 2023 May 31;15(698):eade3856. doi: 10.1126/scitranslmed.ade3856. Epub 2023 May 31. Sci Transl Med. 2023. PMID: 37256935

2

Lentiviral vector-mediated gene transfer in T cells from Wiskott-Aldrich syndrome patients leads to functional correction.

Dupré L, Trifari S, Follenzi A, Marangoni F, Lain de Lera T, Bernad A, Martino S, Tsuchiya S, Bordignon C, Naldini L, Aiuti A, Roncarolo MG. Dupré L, et al. Among authors: naldini l. Mol Ther. 2004 Nov;10(5):903-15. doi: 10.1016/j.ymthe.2004.08.008. Mol Ther. 2004. PMID: 15509508 Free article.

3

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS, Sampaolesi M, Naldini L. De Palma M, et al. Among authors: naldini l. Cancer Cell. 2005 Sep;8(3):211-26. doi: 10.1016/j.ccr.2005.08.002. Cancer Cell. 2005. PMID: 16169466 Free article.

4

Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation.

Dupré L, Marangoni F, Scaramuzza S, Trifari S, Hernández RJ, Aiuti A, Naldini L, Roncarolo MG. Dupré L, et al. Among authors: naldini l. Hum Gene Ther. 2006 Mar;17(3):303-13. doi: 10.1089/hum.2006.17.303. Hum Gene Ther. 2006. PMID: 16544979

5

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.

Brown BD, Venneri MA, Zingale A, Sergi Sergi L, Naldini L. Brown BD, et al. Among authors: naldini l. Nat Med. 2006 May;12(5):585-91. doi: 10.1038/nm1398. Epub 2006 Apr 23. Nat Med. 2006. PMID: 16633348

6

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration.

Montini E, Cesana D, Schmidt M, Sanvito F, Ponzoni M, Bartholomae C, Sergi Sergi L, Benedicenti F, Ambrosi A, Di Serio C, Doglioni C, von Kalle C, Naldini L. Montini E, et al. Among authors: naldini l. Nat Biotechnol. 2006 Jun;24(6):687-96. doi: 10.1038/nbt1216. Epub 2006 May 28. Nat Biotechnol. 2006. PMID: 16732270

7

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects.

Mortellaro A, Hernandez RJ, Guerrini MM, Carlucci F, Tabucchi A, Ponzoni M, Sanvito F, Doglioni C, Di Serio C, Biasco L, Follenzi A, Naldini L, Bordignon C, Roncarolo MG, Aiuti A. Mortellaro A, et al. Among authors: naldini l. Blood. 2006 Nov 1;108(9):2979-88. doi: 10.1182/blood-2006-05-023507. Epub 2006 Jul 11. Blood. 2006. PMID: 16835374 Free article.

8

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. Annoni A, et al. Among authors: naldini l. Blood. 2007 Sep 15;110(6):1788-96. doi: 10.1182/blood-2006-11-059873. Epub 2007 May 10. Blood. 2007. PMID: 17495135 Free article.

9

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

Capotondo A, Cesani M, Pepe S, Fasano S, Gregori S, Tononi L, Venneri MA, Brambilla R, Quattrini A, Ballabio A, Cosma MP, Naldini L, Biffi A. Capotondo A, et al. Among authors: naldini l. Hum Gene Ther. 2007 Sep;18(9):821-36. doi: 10.1089/hum.2007.048. Hum Gene Ther. 2007. PMID: 17845130

10

Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.

Marangoni F, Bosticardo M, Charrier S, Draghici E, Locci M, Scaramuzza S, Panaroni C, Ponzoni M, Sanvito F, Doglioni C, Liabeuf M, Gjata B, Montus M, Siminovitch K, Aiuti A, Naldini L, Dupré L, Roncarolo MG, Galy A, Villa A. Marangoni F, et al. Among authors: naldini l. Mol Ther. 2009 Jun;17(6):1073-82. doi: 10.1038/mt.2009.31. Epub 2009 Mar 3. Mol Ther. 2009. PMID: 19259069 Free PMC article.

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