Sorscher EJ - Search Results

1

Engineered tRNAs suppress nonsense mutations in cells and in vivo.

Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Among authors: sorscher ej. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.

2

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line.

Bedwell DM, Kaenjak A, Benos DJ, Bebok Z, Bubien JK, Hong J, Tousson A, Clancy JP, Sorscher EJ. Bedwell DM, et al. Among authors: sorscher ej. Nat Med. 1997 Nov;3(11):1280-4. doi: 10.1038/nm1197-1280. Nat Med. 1997. PMID: 9359706

3

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary.

Bebök Z, Mazzochi C, King SA, Hong JS, Sorscher EJ. Bebök Z, et al. Among authors: sorscher ej. J Biol Chem. 1998 Nov 6;273(45):29873-8. doi: 10.1074/jbc.273.45.29873. J Biol Chem. 1998. PMID: 9792704 Free article.

4

Hepatocyte growth factor stimulates adenoviral-mediated gene transfer across the apical membrane of epithelial cells.

Burrus JK, Matheson WD, Hong JS, Sorscher EJ, Balkovetz DF. Burrus JK, et al. Among authors: sorscher ej. J Gene Med. 2004 Jun;6(6):624-30. doi: 10.1002/jgm.552. J Gene Med. 2004. PMID: 15170733

5

Cystic fibrosis.

Rowe SM, Miller S, Sorscher EJ. Rowe SM, et al. Among authors: sorscher ej. N Engl J Med. 2005 May 12;352(19):1992-2001. doi: 10.1056/NEJMra043184. N Engl J Med. 2005. PMID: 15888700 No abstract available.

6

Restoration of W1282X CFTR activity by enhanced expression.

Rowe SM, Varga K, Rab A, Bebok Z, Byram K, Li Y, Sorscher EJ, Clancy JP. Rowe SM, et al. Among authors: sorscher ej. Am J Respir Cell Mol Biol. 2007 Sep;37(3):347-56. doi: 10.1165/rcmb.2006-0176OC. Epub 2007 May 31. Am J Respir Cell Mol Biol. 2007. PMID: 17541014 Free PMC article.

7

A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice.

Cormet-Boyaka E, Hong JS, Berdiev BK, Fortenberry JA, Rennolds J, Clancy JP, Benos DJ, Boyaka PN, Sorscher EJ. Cormet-Boyaka E, et al. Among authors: sorscher ej. FASEB J. 2009 Nov;23(11):3743-51. doi: 10.1096/fj.08-127878. Epub 2009 Jul 20. FASEB J. 2009. PMID: 19620404 Free PMC article.

8

Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators.

Pyle LC, Ehrhardt A, Mitchell LH, Fan L, Ren A, Naren AP, Li Y, Clancy JP, Bolger GB, Sorscher EJ, Rowe SM. Pyle LC, et al. Among authors: sorscher ej. Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L587-97. doi: 10.1152/ajplung.00465.2010. Epub 2011 Jul 1. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21724857 Free PMC article.

9

A breath of fresh air.

Rowe SM, Clancy JP, Sorscher EJ. Rowe SM, et al. Among authors: sorscher ej. Sci Am. 2011 Aug;305(2):68-73. doi: 10.1038/scientificamerican0811-68. Sci Am. 2011. PMID: 21827128 No abstract available.

10

Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications.

McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S. McClure M, et al. Among authors: sorscher ej. Protein Eng Des Sel. 2012 Jan;25(1):7-14. doi: 10.1093/protein/gzr054. Epub 2011 Nov 25. Protein Eng Des Sel. 2012. PMID: 22119790 Free PMC article.

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