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355 results

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Page 1
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Miranda-Cervantes A, Fritzen AM, Raun SH, Hodek O, Møller LLV, Johann K, Deisen L, Gregorevic P, Gudiksen A, Artati A, Adamski J, Andersen NR, Sigvardsen CM, Carl CS, Voldstedlund CT, Kjøbsted R, Hauck SM, Schjerling P, Jensen TE, Cebrian-Serrano A, Jähnert M, Gottmann P, Burtscher I, Lickert H, Pilegaard H, Schürmann A, Tschöp MH, Moritz T, Müller TD, Sylow L, Kiens B, Richter EA, Kleinert M. Miranda-Cervantes A, et al. Among authors: tschop mh. Nat Commun. 2025 Jan 2;16(1):345. doi: 10.1038/s41467-024-55036-w. Nat Commun. 2025. PMID: 39746949 Free PMC article.
GLP-1 programs the neurovascular landscape.
Chen B, Yu X, Horvath-Diano C, Ortuño MJ, Tschöp MH, Jastreboff AM, Schneeberger M. Chen B, et al. Among authors: tschop mh. Cell Metab. 2024 Oct 1;36(10):2173-2189. doi: 10.1016/j.cmet.2024.09.003. Cell Metab. 2024. PMID: 39357509 Review.
Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy.
Sánchez-Garrido MA, Serrano-López V, Ruiz-Pino F, Vázquez MJ, Rodríguez-Martín A, Torres E, Velasco I, Rodríguez AB, Chicano-Gálvez E, Mora-Ortiz M, Ohlsson C, Poutanen M, Pinilla L, Gaytán F, Douros JD, Yang B, Müller TD, DiMarchi RD, Tschöp MH, Finan B, Tena-Sempere M. Sánchez-Garrido MA, et al. Among authors: tschop mh. Nat Commun. 2024 Oct 1;15(1):8498. doi: 10.1038/s41467-024-52898-y. Nat Commun. 2024. PMID: 39353946 Free PMC article.
HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice.
Contreras RE, Gruber T, González-García I, Schriever SC, De Angelis M, Mallet N, Bernecker M, Legutko B, Kabra D, Schmidt M, Tschöp MH, Gutierrez-Aguilar R, Mellor J, García-Cáceres C, Pfluger PT. Contreras RE, et al. Among authors: tschop mh. Mol Metab. 2024 Dec;90:102033. doi: 10.1016/j.molmet.2024.102033. Epub 2024 Sep 19. Mol Metab. 2024. PMID: 39304061 Free PMC article.
Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease.
Sachs S, Götz A, Finan B, Feuchtinger A, DiMarchi RD, Döring Y, Weber C, Tschöp MH, Müller TD, Hofmann SM. Sachs S, et al. Among authors: tschop mh. Cardiovasc Diabetol. 2024 Sep 12;23(1):341. doi: 10.1186/s12933-024-02407-8. Cardiovasc Diabetol. 2024. PMID: 39267039 Free PMC article. No abstract available.
Transforming obesity: The advancement of multi-receptor drugs.
Kusminski CM, Perez-Tilve D, Müller TD, DiMarchi RD, Tschöp MH, Scherer PE. Kusminski CM, et al. Among authors: tschop mh. Cell. 2024 Jul 25;187(15):3829-3853. doi: 10.1016/j.cell.2024.06.003. Cell. 2024. PMID: 39059360 Review.
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice.
Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker DJ, Finan B, Grandl G, Gutgesell R, Hofmann SM, Khalil A, Liu X, Cota P, Bakhti M, Czarnecki O, Bastidas-Ponce A, Lickert H, Kang L, Maity G, Novikoff A, Parlee S, Pathak E, Schriever SC, Sterr M, Ussar S, Zhang Q, DiMarchi R, Tschöp MH, Pfluger PT, Douros JD, Müller TD. Akindehin S, et al. Among authors: tschop mh. Mol Metab. 2024 May;83:101915. doi: 10.1016/j.molmet.2024.101915. Epub 2024 Mar 14. Mol Metab. 2024. PMID: 38492844 Free PMC article.
Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
Grandl G, Collden G, Feng J, Bhattacharya S, Klingelhuber F, Schomann L, Bilekova S, Ansarullah, Xu W, Far FF, Tost M, Gruber T, Bastidas-Ponce A, Zhang Q, Novikoff A, Liskiewicz A, Liskiewicz D, Garcia-Caceres C, Feuchtinger A, Tschöp MH, Krahmer N, Lickert H, Müller TD. Grandl G, et al. Among authors: tschop mh. Nat Metab. 2024 Mar;6(3):448-457. doi: 10.1038/s42255-024-00991-3. Epub 2024 Feb 28. Nat Metab. 2024. PMID: 38418586 Free PMC article.
Seeking satiety: From signals to solutions.
Tschöp MH, Friedman JM. Tschöp MH, et al. Sci Transl Med. 2023 Nov 22;15(723):eadh4453. doi: 10.1126/scitranslmed.adh4453. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992155 Review.
355 results