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Page 1
Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase.
Kissai M, Chin EN, Martinez-Péna F, Sulpizio AL, Stout P, Usui I, Barmare F, Sanchez B, Esquenazi E, Stanfield RL, Wilson IA, Lairson LL. Kissai M, et al. Among authors: stanfield rl. Bioorg Med Chem Lett. 2024 Nov 7:130007. doi: 10.1016/j.bmcl.2024.130007. Online ahead of print. Bioorg Med Chem Lett. 2024. PMID: 39521150
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Sewall LM, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Altman PX, et al. Among authors: stanfield rl. PLoS Pathog. 2024 Sep 9;20(9):e1012042. doi: 10.1371/journal.ppat.1012042. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39250525 Free PMC article.
A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers.
Lee YZ, Han J, Zhang YN, Ward G, Gomes KB, Auclair S, Stanfield RL, He L, Wilson IA, Zhu J. Lee YZ, et al. Among authors: stanfield rl. bioRxiv [Preprint]. 2024 Mar 8:2024.03.07.583986. doi: 10.1101/2024.03.07.583986. bioRxiv. 2024. PMID: 38496645 Free PMC article. Preprint.
Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Sun X, Ferguson JA, Yang K, Stanfield RL, Dyson HJ, Wright PE. Sun X, et al. Among authors: stanfield rl. bioRxiv [Preprint]. 2024 Mar 1:2024.02.26.582172. doi: 10.1101/2024.02.26.582172. bioRxiv. 2024. Update in: Protein Sci. 2024 Sep;33(9):e5101. doi: 10.1002/pro.5101. PMID: 38464206 Free PMC article. Updated. Preprint.
Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Altman PX, et al. Among authors: stanfield rl. bioRxiv [Preprint]. 2024 Feb 14:2024.02.13.580058. doi: 10.1101/2024.02.13.580058. bioRxiv. 2024. Update in: PLoS Pathog. 2024 Sep 9;20(9):e1012042. doi: 10.1371/journal.ppat.1012042. PMID: 38405899 Free PMC article. Updated. Preprint.
Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins.
Khalek IS, Senji Laxme RR, Nguyen YTK, Khochare S, Patel RN, Woehl J, Smith JM, Saye-Francisco K, Kim Y, Misson Mindrebo L, Tran Q, Kędzior M, Boré E, Limbo O, Verma M, Stanfield RL, Menzies SK, Ainsworth S, Harrison RA, Burton DR, Sok D, Wilson IA, Casewell NR, Sunagar K, Jardine JG. Khalek IS, et al. Among authors: stanfield rl. Sci Transl Med. 2024 Feb 21;16(735):eadk1867. doi: 10.1126/scitranslmed.adk1867. Epub 2024 Feb 21. Sci Transl Med. 2024. PMID: 38381847
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Huang R, Warner Jenkins G, Kim Y, Stanfield RL, Singh A, Martinez-Yamout M, Kroon GJ, Torres JL, Jackson AM, Kelley A, Shaabani N, Zeng B, Bacica M, Chen W, Warner C, Radoicic J, Joh J, Dinali Perera K, Sang H, Kim T, Yao J, Zhao F, Sok D, Burton DR, Allen J, Harriman W, Mwangi W, Chung D, Teijaro JR, Ward AB, Dyson HJ, Wright PE, Wilson IA, Chang KO, McGregor D, Smider VV. Huang R, et al. Among authors: stanfield rl. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2303455120. doi: 10.1073/pnas.2303455120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722054 Free PMC article.
Divergent Total Synthesis and Characterization of Maxamycins.
Moore MJ, Qin P, Keith DJ, Wu ZC, Jung S, Chatterjee S, Tan C, Qu S, Cai Y, Stanfield RL, Boger DL. Moore MJ, et al. Among authors: stanfield rl. J Am Chem Soc. 2023 Jun 14;145(23):12837-12852. doi: 10.1021/jacs.3c03710. Epub 2023 Jun 6. J Am Chem Soc. 2023. PMID: 37278486 Free PMC article.
150 results