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SCCA1/SERPINB3 suppresses antitumor immunity and blunts therapy-induced T cell responses via STAT-dependent chemokine production.
Chen L, Shi V, Wang S, Sun L, Freeman R, Yang J, Inkman MJ, Ghosh S, Ruiz F, Jayachandran K, Huang Y, Luo J, Zhang J, Cosper P, Luke CJ, Spina CS, Grigsby PW, Schwarz JK, Markovina S. Chen L, et al. Among authors: cosper p. J Clin Invest. 2023 Aug 1;133(15):e163841. doi: 10.1172/JCI163841. J Clin Invest. 2023. PMID: 37279067 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 37784359
Chromosomal instability increases radiation sensitivity.
Cosper PF, Paracha M, Jones KM, Hrycyniak L, Henderson L, Bryan A, Eyzaguirre D, McCunn E, Boulanger E, Wan J, Nickel KP, Horner V, Hu R, Harari PM, Kimple RJ, Weaver BA. Cosper PF, et al. bioRxiv [Preprint]. 2024 Sep 19:2024.09.13.612942. doi: 10.1101/2024.09.13.612942. bioRxiv. 2024. PMID: 39345631 Free PMC article. Preprint.
HPV16 E6 induces chromosomal instability due to polar chromosomes caused by E6AP-dependent degradation of the mitotic kinesin CENP-E.
Cosper PF, Hrycyniak LCF, Paracha M, Lee DL, Wan J, Jones K, Bice SA, Nickel K, Mallick S, Taylor AM, Kimple RJ, Lambert PF, Weaver BA. Cosper PF, et al. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2216700120. doi: 10.1073/pnas.2216700120. Epub 2023 Mar 29. Proc Natl Acad Sci U S A. 2023. PMID: 36989302 Free PMC article.
SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses.
Chen L, Shi V, Wang S, Freeman R, Ruiz F, Jayachandran K, Zhang J, Cosper P, Sun L, Luke CJ, Spina C, Grigsby PW, Schwarz JK, Markovina S. Chen L, et al. Among authors: cosper p. bioRxiv [Preprint]. 2023 Feb 3:2023.02.01.526675. doi: 10.1101/2023.02.01.526675. bioRxiv. 2023. PMID: 36778224 Free PMC article. Preprint.
52 results