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Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore BB, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V. Chen X, et al. Among authors: goertsen d. Nat Commun. 2023 Jun 8;14(1):3345. doi: 10.1038/s41467-023-38582-7. Nat Commun. 2023. PMID: 37291094 Free PMC article.
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan E, Huang SF, Kumar SR, Arokiaraj CM, Plattner V, Campos LJ, Mich J, Monet D, Ngo V, Ding X, Omstead V, Weed N, Bishaw Y, Gore B, Lein ES, Akrami A, Miller C, Levi BP, Keller A, Ting JT, Fox AS, Eroglu C, Gradinaru V. Chen X, et al. Among authors: goertsen d. bioRxiv [Preprint]. 2023 Jan 13:2023.01.12.523844. doi: 10.1101/2023.01.12.523844. bioRxiv. 2023. Update in: Nat Commun. 2023 Jun 8;14(1):3345. doi: 10.1038/s41467-023-38582-7 PMID: 36711773 Free PMC article. Updated. Preprint.
Adeno-Associated Virus Toolkit to Target Diverse Brain Cells.
Challis RC, Ravindra Kumar S, Chen X, Goertsen D, Coughlin GM, Hori AM, Chuapoco MR, Otis TS, Miles TF, Gradinaru V. Challis RC, et al. Among authors: goertsen d. Annu Rev Neurosci. 2022 Jul 8;45:447-469. doi: 10.1146/annurev-neuro-111020-100834. Epub 2022 Apr 19. Annu Rev Neurosci. 2022. PMID: 35440143 Free article. Review.