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The first in-human study to evaluate the antiplatelet properties of the clopidogrel conjugate DT-678 in acute coronary syndrome patients and healthy volunteers.
Liu Z, Liu S, Gong Y, Chi X, Wang T, Fan F, Qu C, Lou Y, Zhang L, Zhang B, Yang F, Mohetaboer M, Wang J, Qiu L, Miao L, Lu Y, You R, He P, Li Y, Yi T, Weng H, Xia Y, Wang C, Shi Q, Wang Z, Jiang Y, Li Y, Han C, Wang Y, Wang X, Yang C, Chen YE, Eitzman DT, Zhang H, Li J. Liu Z, et al. Br J Pharmacol. 2025 Jan;182(1):131-141. doi: 10.1111/bph.17355. Epub 2024 Oct 4. Br J Pharmacol. 2025. PMID: 39367653 Clinical Trial.
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