Ottaviani A - Search Results

1

Neutralizing IFNγ improves safety without compromising efficacy of CAR-T cell therapy in B-cell malignancies.

Manni S, Del Bufalo F, Merli P, Silvestris DA, Guercio M, Caruso S, Reddel S, Iaffaldano L, Pezzella M, Di Cecca S, Sinibaldi M, Ottaviani A, Quadraccia MC, Aurigemma M, Sarcinelli A, Ciccone R, Abbaszadeh Z, Ceccarelli M, De Vito R, Lodi MC, Cefalo MG, Mastronuzzi A, De Angelis B, Locatelli F, Quintarelli C. Manni S, et al. Among authors: ottaviani a. Nat Commun. 2023 Jun 9;14(1):3423. doi: 10.1038/s41467-023-38723-y. Nat Commun. 2023. PMID: 37296093 Free PMC article.

2

Rolling circle amplification-based detection of human topoisomerase I activity on magnetic beads.

Zuccaro L, Tesauro C, Cerroni B, Ottaviani A, Knudsen BR, Balasubramanian K, Desideri A. Zuccaro L, et al. Among authors: ottaviani a. Anal Biochem. 2014 Apr 15;451:42-4. doi: 10.1016/j.ab.2014.02.003. Epub 2014 Feb 11. Anal Biochem. 2014. PMID: 24525043

3

Real-time analysis of cleavage and religation activity of human topoisomerase 1 based on ternary fluorescence resonance energy transfer DNA substrate.

Wang Z, Ouyang H, Tesauro C, Ottaviani A, He Y, Fiorani P, Xie H, Desideri A, Fu Z. Wang Z, et al. Among authors: ottaviani a. Arch Biochem Biophys. 2018 Apr 2;643:1-6. doi: 10.1016/j.abb.2018.02.006. Epub 2018 Feb 16. Arch Biochem Biophys. 2018. PMID: 29458004

4

From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica.

Ottaviani A, Welsch J, Agama K, Pommier Y, Desideri A, Baker BJ, Fiorani P. Ottaviani A, et al. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1404-1410. doi: 10.1080/14756366.2022.2078320. J Enzyme Inhib Med Chem. 2022. PMID: 35603503 Free PMC article.

5

Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages.

Raniolo S, Vindigni G, Ottaviani A, Unida V, Iacovelli F, Manetto A, Figini M, Stella L, Desideri A, Biocca S. Raniolo S, et al. Among authors: ottaviani a. Nanomedicine. 2018 Jun;14(4):1181-1190. doi: 10.1016/j.nano.2018.02.002. Epub 2018 Feb 17. Nanomedicine. 2018. PMID: 29458213

6

Replacement of the human topoisomerase linker domain with the plasmodial counterpart renders the enzyme camptothecin resistant.

Arnò B, D'Annessa I, Tesauro C, Zuccaro L, Ottaviani A, Knudsen B, Fiorani P, Desideri A. Arnò B, et al. Among authors: ottaviani a. PLoS One. 2013 Jul 2;8(7):e68404. doi: 10.1371/journal.pone.0068404. Print 2013. PLoS One. 2013. PMID: 23844196 Free PMC article.

7

Engineering a responsive DNA triple helix into an octahedral DNA nanostructure for a reversible opening/closing switching mechanism: a computational and experimental integrated study.

Ottaviani A, Iacovelli F, Idili A, Falconi M, Ricci F, Desideri A. Ottaviani A, et al. Nucleic Acids Res. 2018 Nov 2;46(19):9951-9959. doi: 10.1093/nar/gky857. Nucleic Acids Res. 2018. PMID: 30247614 Free PMC article.

8

Simulative and Experimental Characterization of a pH-Dependent Clamp-like DNA Triple-Helix Nanoswitch.

Iacovelli F, Idili A, Benincasa A, Mariottini D, Ottaviani A, Falconi M, Ricci F, Desideri A. Iacovelli F, et al. Among authors: ottaviani a. J Am Chem Soc. 2017 Apr 19;139(15):5321-5329. doi: 10.1021/jacs.6b11470. Epub 2017 Apr 7. J Am Chem Soc. 2017. PMID: 28365993

9

DNA hairpins promote temperature controlled cargo encapsulation in a truncated octahedral nanocage structure family.

Franch O, Iacovelli F, Falconi M, Juul S, Ottaviani A, Benvenuti C, Biocca S, Ho YP, Knudsen BR, Desideri A. Franch O, et al. Among authors: ottaviani a. Nanoscale. 2016 Jul 21;8(27):13333-41. doi: 10.1039/c6nr01806h. Epub 2016 Jun 24. Nanoscale. 2016. PMID: 27341703

10

Cow Milk Extracellular Vesicle Effects on an In Vitro Model of Intestinal Inflammation.

Mecocci S, Ottaviani A, Razzuoli E, Fiorani P, Pietrucci D, De Ciucis CG, Dei Giudici S, Franzoni G, Chillemi G, Cappelli K. Mecocci S, et al. Among authors: ottaviani a. Biomedicines. 2022 Feb 28;10(3):570. doi: 10.3390/biomedicines10030570. Biomedicines. 2022. PMID: 35327370 Free PMC article.

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