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Preclinical evaluation of the SARS-CoV-2 Mpro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir.
Chen X, Huang X, Ma Q, Kuzmič P, Zhou B, Zhang S, Chen J, Xu J, Liu B, Jiang H, Zhang W, Yang C, Wu S, Huang J, Li H, Long C, Zhao X, Xu H, Sheng Y, Guo Y, Niu C, Xue L, Xu Y, Liu J, Zhang T, Spencer J, Zhu Z, Deng W, Chen X, Chen SH, Zhong N, Xiong X, Yang Z. Chen X, et al. Among authors: zhou b. Nat Microbiol. 2024 Apr;9(4):1075-1088. doi: 10.1038/s41564-024-01618-9. Epub 2024 Mar 29. Nat Microbiol. 2024. PMID: 38553607 Free PMC article.
Genome-wide DNA methylation and mRNA transcription analysis revealed aberrant gene regulation pathways in dermatomyositis and polymyositis patients.
Luo H, Zhu H, Bao D, Xiao Y, Zhou B, Xiao G, Zhang L, Gao S, Li L, Liu Y, Liu D, Wu J, Meng Q, Meng M, Chen T, Zuo X, Li Q, Zhang H. Luo H, et al. Among authors: zhou b. Chin Med J (Engl). 2024 Nov 5. doi: 10.1097/CM9.0000000000003337. Online ahead of print. Chin Med J (Engl). 2024. PMID: 39497373 No abstract available.
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