Gamage T - Search Results

1

Axially Chiral Cannabinoids: Design, Synthesis, and Cannabinoid Receptor Affinity.

Kearney SE, Gangano AJ, Barrus DG, Rehrauer KJ, Reid TR, Navaratne PV, Tracy EK, Roitberg A, Ghiviriga I, Cunningham CW, Gamage T, Grenning AJ. Kearney SE, et al. Among authors: gamage t. J Am Chem Soc. 2023 Jun 28;145(25):13581-13591. doi: 10.1021/jacs.3c00129. Epub 2023 Jun 14. J Am Chem Soc. 2023. PMID: 37314891 Free PMC article.

2

Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators.

Nguyen T, Gamage TF, Decker AM, Barrus D, Langston TL, Li JX, Thomas BF, Zhang Y. Nguyen T, et al. Among authors: gamage tf. J Med Chem. 2019 Nov 14;62(21):9806-9823. doi: 10.1021/acs.jmedchem.9b01161. Epub 2019 Oct 24. J Med Chem. 2019. PMID: 31596583 Free PMC article.

3

In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018.

Gamage TF, Barrus DG, Kevin RC, Finlay DB, Lefever TW, Patel PR, Grabenauer MA, Glass M, McGregor IS, Wiley JL, Thomas BF. Gamage TF, et al. Pharmacol Biochem Behav. 2020 Jun;193:172918. doi: 10.1016/j.pbb.2020.172918. Epub 2020 Apr 2. Pharmacol Biochem Behav. 2020. PMID: 32247816 Free PMC article.

4

Sex, species and age: Effects of rodent demographics on the pharmacology of ∆⁹-tetrahydrocanabinol.

Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF. Wiley JL, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110064. doi: 10.1016/j.pnpbp.2020.110064. Epub 2020 Aug 15. Prog Neuropsychopharmacol Biol Psychiatry. 2021. PMID: 32810571 Free PMC article.

5

Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids.

Nguyen T, Gamage TF, Decker AM, Finlay DB, Langston TL, Barrus D, Glass M, Harris DL, Zhang Y. Nguyen T, et al. Among authors: gamage tf. Bioorg Med Chem. 2021 Jul 1;41:116215. doi: 10.1016/j.bmc.2021.116215. Epub 2021 May 12. Bioorg Med Chem. 2021. PMID: 34015703 Free PMC article.

6

Development of 3-(4-Chlorophenyl)-1-(phenethyl)urea Analogues as Allosteric Modulators of the Cannabinoid Type-1 Receptor: RTICBM-189 is Brain Penetrant and Attenuates Reinstatement of Cocaine-Seeking Behavior.

Nguyen T, Gamage TF, Finlay DB, Decker AM, Langston TL, Barrus D, Glass M, Li JX, Kenakin TP, Zhang Y. Nguyen T, et al. Among authors: gamage tf. J Med Chem. 2022 Jan 13;65(1):257-270. doi: 10.1021/acs.jmedchem.1c01432. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34929081 Free PMC article.

7

Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018.

Finlay DB, Nguyen T, Gamage TF, Chen S, Barrus DG, Patel PR, Thomas BF, Wiley JL, Zhang Y, Glass M. Finlay DB, et al. Among authors: gamage tf. Pharmacol Res Perspect. 2022 Feb;10(1):e00901. doi: 10.1002/prp2.901. Pharmacol Res Perspect. 2022. PMID: 35041297 Free PMC article.

8

Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice.

Wiley JL, Marusich JA, Blough BE, Namjoshi O, Brackeen M, Akinfiresoye LR, Walker TD, Prioleau C, Barrus DG, Gamage TF. Wiley JL, et al. Among authors: gamage tf. Prog Neuropsychopharmacol Biol Psychiatry. 2024 Jun 8;132:110984. doi: 10.1016/j.pnpbp.2024.110984. Epub 2024 Feb 27. Prog Neuropsychopharmacol Biol Psychiatry. 2024. PMID: 38417478

9

Diarylureas Containing 5-Membered Heterocycles as CB₁ Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation.

Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Nguyen T, et al. Among authors: gamage tf. ACS Chem Neurosci. 2019 Jan 16;10(1):518-527. doi: 10.1021/acschemneuro.8b00396. Epub 2018 Sep 20. ACS Chem Neurosci. 2019. PMID: 30188693 Free PMC article.

10

Synthetic Cannabinoid Hydroxypentyl Metabolites Retain Efficacy at Human Cannabinoid Receptors.

Gamage TF, Farquhar CE, McKinnie RJ, Kevin RC, McGregor IS, Trudell ML, Wiley JL, Thomas BF. Gamage TF, et al. J Pharmacol Exp Ther. 2019 Mar;368(3):414-422. doi: 10.1124/jpet.118.254425. Epub 2018 Dec 14. J Pharmacol Exp Ther. 2019. PMID: 30552295 Free PMC article.

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