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Page 1
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Bayerl F, Meiser P, Donakonda S, Hirschberger A, Lacher SB, Pedde AM, Hermann CD, Elewaut A, Knolle M, Ramsauer L, Rudolph TJ, Grassmann S, Öllinger R, Kirchhammer N, Trefny M, Anton M, Wohlleber D, Höchst B, Zaremba A, Krüger A, Rad R, Obenauf AC, Schadendorf D, Zippelius A, Buchholz VR, Schraml BU, Böttcher JP. Bayerl F, et al. Among authors: rad r. Immunity. 2023 Jun 13;56(6):1341-1358.e11. doi: 10.1016/j.immuni.2023.05.011. Immunity. 2023. PMID: 37315536 Free article.
The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection.
Moeed A, Thilmany N, Beck F, Puthussery BK, Ortmann N, Haimovici A, Badr MT, Haghighi EB, Boerries M, Öllinger R, Rad R, Kirschnek S, Gentle IE, Donakonda S, Petric PP, Hummel JF, Pfaffendorf E, Zanetta P, Schell C, Schwemmle M, Weber A, Häcker G. Moeed A, et al. Among authors: rad r. Cell Death Differ. 2024 Jul;31(7):924-937. doi: 10.1038/s41418-024-01320-7. Epub 2024 Jun 7. Cell Death Differ. 2024. PMID: 38849575 Free PMC article.
Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity.
Pedde AM, Kim H, Donakonda S, Baumann T, Bayerl F, Meiser P, Hirschberger A, Klement C, Grassmann S, Öllinger R, Hüser N, Hartmann D, Laschinger M, Trapani JA, Zippelius A, Bald T, Wiedemann GM, Rad R, Sun JC, Höchst B, Böttcher JP. Pedde AM, et al. Among authors: rad r. Cell Rep. 2024 Nov 26;43(11):114855. doi: 10.1016/j.celrep.2024.114855. Epub 2024 Nov 13. Cell Rep. 2024. PMID: 39541209 Free article.
High RIPK3 expression is associated with a higher risk of early kidney transplant failure.
Wahida A, Schmaderer C, Büttner-Herold M, Branca C, Donakonda S, Haberfellner F, Torrez C, Schmitz J, Schulze T, Seibt T, Öllinger R, Engleitner T, Haller B, Steiger K, Günthner R, Lorenz G, Yabal M, Bachmann Q, Braunisch MC, Moog P, Matevossian E, Aßfalg V, Thorban S, Renders L, Späth MR, Müller RU, Stippel DL, Weichert W, Slotta-Huspenina J, von Vietinghoff S, Viklicky O, Green DR, Rad R, Amann K, Linkermann A, Bräsen JH, Heemann U, Kemmner S. Wahida A, et al. Among authors: rad r. iScience. 2023 Sep 17;26(10):107879. doi: 10.1016/j.isci.2023.107879. eCollection 2023 Oct 20. iScience. 2023. PMID: 37868627 Free PMC article.
A ONECUT1 regulatory, non-coding region in pancreatic development and diabetes.
Merz S, Senée V, Philippi A, Oswald F, Shaigan M, Führer M, Drewes C, Allgöwer C, Öllinger R, Heni M, Boland A, Deleuze JF, Birkhofer F, Gusmao EG, Wagner M, Hohwieler M, Breunig M, Rad R, Siebert R, Messerer DAC, Costa IG, Alvarez F, Julier C, Kleger A, Heller S. Merz S, et al. Among authors: rad r. Cell Rep. 2024 Nov 26;43(11):114853. doi: 10.1016/j.celrep.2024.114853. Epub 2024 Oct 19. Cell Rep. 2024. PMID: 39427318 Free article.
Ovulation is triggered by a cyclical modulation of gonadotropes into a hyperexcitable state.
Götz V, Qiao S, Das D, Wartenberg P, Wyatt A, Wahl V, Gamayun I, Alasmi S, Fecher-Trost C, Meyer MR, Rad R, Kaltenbacher T, Kattler K, Lipp P, Becherer U, Mollard P, Candlish M, Boehm U. Götz V, et al. Among authors: rad r. Cell Rep. 2023 Jun 27;42(6):112543. doi: 10.1016/j.celrep.2023.112543. Epub 2023 May 23. Cell Rep. 2023. PMID: 37224016 Free article.
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis.
Diehl C, Soberón V, Baygün S, Chu Y, Mandelbaum J, Kraus L, Engleitner T, Rudelius M, Fangazio M, Daniel C, Bortoluzzi S, Helmrath S, Singroul P, Gölling V, Osorio Barrios F, Seyhan G, Oßwald L, Kober-Hasslacher M, Zeng T, Öllinger R, Afzali AM, Korn T, Honarpisheh M, Lech M, Ul Ain Q, Pircher J, Imširović V, Jelenčić V, Wensveen FM, Passerini V, Bärthel S, Bhagat G, Dominguez-Sola D, Saur D, Steiger K, Rad R, Pasqualucci L, Weigert O, Schmidt-Supprian M. Diehl C, et al. Among authors: rad r. Immunity. 2024 Dec 25:S1074-7613(24)00538-7. doi: 10.1016/j.immuni.2024.11.023. Online ahead of print. Immunity. 2024. PMID: 39729992
Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma.
Papargyriou A, Najajreh M, Cook DP, Maurer CH, Bärthel S, Messal HA, Ravichandran SK, Richter T, Knolle M, Metzler T, Shastri AR, Öllinger R, Jasper J, Schmidleitner L, Wang S, Schneeweis C, Ishikawa-Ankerhold H, Engleitner T, Mataite L, Semina M, Trabulssi H, Lange S, Ravichandra A, Schuster M, Mueller S, Peschke K, Schäfer A, Dobiasch S, Combs SE, Schmid RM, Bausch AR, Braren R, Heid I, Scheel CH, Schneider G, Zeigerer A, Luecken MD, Steiger K, Kaissis G, van Rheenen J, Theis FJ, Saur D, Rad R, Reichert M. Papargyriou A, et al. Among authors: rad r. Nat Biomed Eng. 2024 Dec 10. doi: 10.1038/s41551-024-01273-9. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39658630
High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells.
Füchsl F, Untch J, Kavaka V, Zuleger G, Braun S, Schwanzer A, Jarosch S, Vogelsang C, de Andrade Krätzig N, Gosmann D, Öllinger R, Giansanti P, Hiltensperger M, Rad R, Busch DH, Beltrán E, Bräunlein E, Krackhardt AM. Füchsl F, et al. Among authors: rad r. Nat Commun. 2024 Dec 3;15(1):10520. doi: 10.1038/s41467-024-53911-0. Nat Commun. 2024. PMID: 39627205 Free PMC article.
272 results